Recently, BOC Sciences announced that it will provide a new PEGylation technology platform to meet the needs of customers all over the world.
Shirley, United States - October 22, 2020 /MarketersMedia/ —
Recently, BOC Sciences, a well-known chemical and pharmaceutical supplier, announced that it will provide a new PEGylation technology platform to meet the needs of customers all over the world.
PEGylation is a process in which polyethylene glycol polymer chains are covalently and non-covalently linked or fused to molecules and macrostructures, such as drugs and therapeutic proteins,or vesicles. Compared with the unmodified form, PEGylation, by increasing the molecular weight of molecules, can provide several significant pharmacological advantages, such as improving drug solubility, reducing dose frequency without reducing efficacy, potentially reducing toxicity, prolonging cycle life, increasing drug stability, and enhancing protection against protein hydrolysis and degradation. Since the 1970s, PEGylation technology has been evolved for decades and has been successfully applied in therapeutic solutions on the market. In the United States and Europe, more than 10 PEGylated biotherapeutics have been approved.
Applications of PEGylation
The PEGylation process increases the molecular mass of the therapeutic protein, so it can protect the therapeutic protein from proteolytic enzymes and protein degradation.
PEGylation has been proven to effectively improve the heat resistance of protein and peptide drugs. In addition, PEG with larger molecular size is usually more effective in removing protein from renal glomerular filtration, thereby prolonging its plasma half-life.
PEGylation for targeted drug delivery may reduce clearance and enhance delivery of peptide and protein molecules.
PEGylation of microparticles can improve some therapeutic applications, such as bioassay, degradation, and release kinetics, etc.
PEG nanoparticles are the most entrenched drug carriers in clinical applications, and are expected to expand the therapeutic development of the biologics market.
BOC Sciences offers synthetic polyethylene glycol modification and bioconjugation services by site-specific ligation of PEG to peptides, proteins, oligonucleotides, antibodies, lectins, enzymes, toxins, drugs or other small molecules.
For more information about the new PEGylation platform, please visit the website: https://bioconjugation.bocsci.com.
About BOC Sciences
BOC Sciences has been closely involved with drug discovery, chemistry and life science by supplying a comprehensive collection of chemicals to researchers, such as inhibitors, metabolites, impurities and natural compounds. Meanwhile, it also provides a wide range of services through all stages of drug R&D to support the pharmaceutical industry, like custom synthesis of chemicals, isotope labeling, formulation service, antibody drug conjugates, chiral synthesis and resolution.
Contact Info:
Name: Alex Brown
Email: Send Email
Organization: BOC Sciences
Address: 45-16 Ramsey Road Shirley, NY 11967, USA
Website: https://www.bocsci.com
Source URL: https://marketersmedia.com/boc-sciences-provides-a-new-pegylation-platform/88982137
Source: MarketersMedia
Release ID: 88982137
