CStone Files Taiwan NDA for Precision-Med GIST Candidate

Suzhou CStone Pharma filed an NDA in Taiwan for avapritinib, a precision therapy for gastrointestinal stromal tumors (GIST). The candidate is indicated for adult patients with unresectable or metastatic GIST harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation, including PDGFRA D842V mutations. Avapritinib produced an ORR of 84% in the patient population against a 0% ORR for other TKI drugs. In 2018, CStone in-licensed greater China rights to avapritinib in a $386 million, three-drug deal with Blueprint Medicines of Cambridge, MA. More details.... Stock Symbols: (HK: 2616) (NSDQ: BPMC) Share this with colleagues: // //