c50352_nq.htm -- Converted by SEC Publisher, created by BCL Technologies Inc., for SEC Filing

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM N-Q

QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED
MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number 811-21702

Name of Fund: BlackRock Health Sciences Trust

Fund Address: 100 Bellevue Parkway, Wilmington, DE 19809

Name and address of agent for service: Robert S. Kapito, President, BlackRock Health Sciences Trust, 40 East 52nd Street, New York, NY 10022.

Registrant’s telephone number, including area code: (888) 825-2257

Date of fiscal year end: 10/31/2007

Date of reporting period: 05/01/2007 – 07/31/2007


Item 1 – Schedule of Investments


PORTFOLIO OF INVESTMENTS (unaudited)
JULY 31, 2007
BlackRock Health Sciences Trust (BME)
(Percentages shown are based on Net Assets)


Shares
   
Description
Value
 
      LONG-TERM INVESTMENTS—94.8%      
      Common Stocks—94.8%      
      Biotechnology—21.4%      
186,600     Alexion Pharmaceuticals, Inc.
$
10,852,656  
37,800     Amgen, Inc.   2,031,372  
89,900     Applera Corp. - Celera Group   1,080,598  
40,700     Arqule, Inc.   231,176  
71,300 1   Celgene Corp.   4,317,928  
61,000 1   Charles River Laboratories Intl., Inc.   3,121,980  
78,300 1   Genentech, Inc.   5,823,954  
54,500 1   Halozyme Therapeutics, Inc.   438,180  
85,700 1   Integra LifeSciences Holdings Corp.   4,255,005  
90,167 1   InterMune, Inc.   1,925,066  
191,718 1   Kosan Biosciences, Inc.   797,547  
28,100 1   Millipore Corp.   2,208,941  
144,700 1   Myriad Genetics, Inc.   5,408,886  
87,337 1   NicOx S.A.   2,036,271  
21,300 1   Seattle Genetics, Inc.   202,989  
      Total Biotechnology   44,732,549  
      Commercial Services—0.4%      
28,200 1   PRA Intl.   815,826  
      Distribution/Wholesale—1.3%      
23,500 1   MWI Veterinary Supply, Inc.   908,745  
48,600     Owen & Minor, Inc.   1,868,670  
      Total Distribution/Wholesale   2,777,415  
      Electronics—2.2%      
41,200 1   Varian, Inc.   2,477,768  
35,800 1   Waters Corp.   2,085,708  
      Total Electronics   4,563,476  
      Healthcare Products—27.9%      
31,300     Alcon, Inc.   4,272,450  
98,600     Baxter Intl., Inc.   5,186,360  
106,500     Becton Dickinson & Co.   8,132,340  
97,300 1   Cyberonics, Inc.   1,362,200  
110,700     Dentsply Intl., Inc.   4,039,443  
40,100     Edwards Lifesciences Corp.   1,842,996  
86,500     Johnson & Johnson   5,233,250  
22,500 1   Kyphon, Inc.   1,476,450  
135,200     Medtronic, Inc.   6,850,584  
52,600 1   SenoRx, Inc.   511,798  
37,000 1   St. Jude Medical, Inc.   1,596,180  
132,500     Stryker Corp.   8,271,975  
133,600 1   Thoratec Corp.   2,593,176  
20,800 1   Ventana Medical Systems, Inc.   1,733,472  
211,500 1   Wright Medical Group, Inc.   5,120,415  
      Total Healthcare Products   58,223,089  
      Healthcare Services—7.6%      
73,700     Aetna, Inc.   3,542,759  
27,900 1   Covance, Inc.   1,968,903  
87,800     Manor Care, Inc.   5,562,130  
20,600 1   Pediatrix Medical Group, Inc.   1,111,576  
24,083 1   Psychiatric Solutions, Inc.   820,990  
56,300     UnitedHealth Group, Inc.   2,726,609  
      Total Healthcare Services   15,732,967  
      Pharmaceuticals—32.3%      
103,100     Abbott Laboratories   5,226,139  
199,438 1   BioMarin Pharmaceuticals, Inc.   3,601,850  
101,700     Bristol-Myers Squibb Co.   2,889,297  
13,300 1   Cephalon, Inc.   999,362  
137,000 1   Gilead Sciences, Inc.   5,100,510  
69,700 1   ImClone Systems, Inc.   2,293,130  
233,200 2   Merck & Co., Inc.   11,578,380  
31,000     Novartis AG (ADR)   1,672,450  
28,065 1   Onyx Pharmaceuticals, Inc.   780,488  
195,500 2   Pfizer, Inc.   4,596,205  
66,500 1   Poniard Pharmaceuticals, Inc.   385,700  
7,200 1   Pozen, Inc.   119,880  
63,650     Roche Holding AG   11,272,817  
184,500     Schering-Plough Corp.   5,265,630  
37,000     Teva Pharmaceutical Industries Ltd. (ADR)   1,554,740  
74,700     Tongjitang Chinese Medicines Co. (ADR)   888,183  
10,100 1   United Therapeutics Corp.   700,536  
177,000     Wyeth   8,588,040  
      Total Pharmaceuticals   67,513,337  
      Technology—1.5%      
89,100     CVS Caremark Corp.   3,135,429  
      Software—0.2%      
25,200 1   Phase Forward, Inc.   433,188  
      Total Long-Term Investments      
      (cost $180,356,720)   197,927,276  
      MONEY MARKET FUND—4.2%      
8,809,279 3   Fidelity Institutional Money Market Prime Portfolio, 4.99% (cost $8,809,279)   8,809,279  
Contracts
       
      OUTSTANDING CALL OPTIONS PURCHASED—0.0%      
10,000     Elan Corp. Plc (ADR), strike price $23, expires 11/16/07   10,626  
10,000     Regeneron Pharmaceuticals, Inc., strike price $29, expires 11/16/07   1,867  
23,500     Wyeth, strike price $59, expires 11/16/07   383  
12,000     Zimmer Holdings, Inc., strike price $90, expires 11/16/07   11,964  
      Total Outstanding Call Options Purchased      
      (cost $45,707)   24,840  
      Total Investments before outstanding options written      
      (cost $189,211,7064)   206,761,395  
      OUTSTANDING OPTIONS WRITTEN—(1.0)%      
      OUTSTANDING CALL OPTIONS WRITTEN—(0.9)%      
(250 )   Abbott Laboratories, strike price $58.50, expires 11/02/07   (10,632 )
(15,000 )   Aetna, Inc., strike price $55.25, expires 11/16/07   (7,551 )
(50 )   Alcon, Inc., strike price $150, expires 11/19/07   (19,000 )
(450 )   Alexion Pharmaceuticals, Inc., strike price $50, expires 08/20/07   (387,000 )
(150 )   Alexion Pharmaceuticals, Inc., strike price $50, expires 11/19/07   (165,000 )
(25,000 )   Alexion Pharmaceuticals, Inc., strike price $61, expires 11/16/07   (108,735 )
(11,000 )   Amgen, Inc., strike price $58.56, expires 11/16/07   (17,410 )
(150 )   Applera Corp. - Celera Group, strike price $15, expires 12/24/07   (8,250 )
(200 )   Baxter Intl., Inc., strike price $57.50, expires 08/20/07   (3,000 )
(10,000 )   Baxter Intl., Inc., strike price $60.50, expires 11/16/07   (6,903 )
(12,500 )   Becton Dickinson & Co., strike price $77.84, expires 11/16/07   (36,645 )
(100 )   Becton Dickinson & Co., strike price $80, expires 12/24/07   (28,500 )
(250 )   BioMarin Pharmaceuticals, Inc., strike price $20, expires 11/02/07   (18,858 )
(200 )   Bristol-Myers Squibb Co., strike price $32.50, expires 12/24/07   (10,000 )
(11,000 )   Celgene Corp., strike price $59.89, expires 11/16/07   (61,822 )
(20 )   Cephalon, Inc., strike price $90, expires 11/19/07   (1,200 )
(100 )   Charles River Laboratories Intl., Inc., strike price $55, expires 08/20/07   (8,000 )

1


BlackRock Health Sciences Trust (BME) (continued)
(Percentages shown are based on Net Assets)

Contracts
Description
Value
 
      OUTSTANDING CALL OPTIONS WRITTEN— (cont'd)      
(15,000
)   Charles River Laboratories Intl., Inc., strike price $56.50, expires 11/16/07 $ (23,726 )
(50 )   Covance, Inc., strike price $70, expires 11/19/07   (27,500 )
(30 )   Covance, Inc., strike price $75, expires 11/19/07   (8,700 )
(100 )   CVS Caremark Corp., strike price $40, expires 08/20/07   (500 )
(10,000 )   CVS Caremark Corp., strike price $41, expires 11/16/07   (9,518 )
(20,000 )   Cyberonics, Inc., strike price $20.50, expires 11/16/07   (2,844 )
(300 )   Dentsply Intl., Inc., strike price $36, expires 11/02/07   (70,899 )
(50 )   Edwards Lifesciences Corp., strike price $50, expires 08/20/07   (750 )
(50 )   Edwards Lifesciences Corp., strike price $55, expires 11/19/07   (1,500 )
(10,000 )   Elan Corp. Plc (ADR), strike price $23.55, expires 11/16/07   (9,481 )
(20,000 )   Genentech, Inc., strike price $78.25, expires 09/21/07   (16,914 )
(400 )   Gilead Sciences, Inc., strike price $42.50, expires 08/20/07   (4,000 )
(20,000 )   Gilead Sciences, Inc., strike price $45.50, expires 11/16/07   (6,764 )
(100 )   Halozyme Therapeutics, Inc., strike price $10, expires 12/24/07   (7,500 )
(50 )   ImClone Systems, Inc., strike price $50, expires 11/19/07   (1,000 )
(40 )   Integra Lifesciences Holdings Corp., strike price $50, expires 09/24/07   (9,400 )
(15,000 )   Integra Lifesciences Holdings Corp., strike price $55.25, expires 11/16/07   (13,707 )
(20,000 )   InterMune, Inc., strike price $30.50, expires 11/16/07   (3,700 )
(50 )   Kyphon, Inc., strike price $50, expires 12/24/07   (88,500 )
(200 )   Manor Care, Inc., strike price $70, expires 08/20/07   (1,000 )
(250 )   Medtronic, Inc., strike price $55, expires 11/19/07   (28,750 )
(100 )   Medtronic, Inc., strike price $57.50, expires 11/19/07   (6,000 )
(300 )   Merck & Co., Inc., strike price $50.50, expires 11/02/07   (68,883 )
(500 )   Merck & Co., Inc., strike price $57, expires 11/02/07   (27,260 )
(50 )   Millipore Corp., strike price $80, expires 10/22/07   (20,000 )
(250 )   Myriad Genetics, Inc., strike price $40, expires 11/19/07   (57,500 )
(100 )   Myriad Genetics, Inc., strike price $45, expires 11/19/07   (9,000 )
(16,000 )   NicOx S.A., strike price 21.30 EUR, expires 11/06/07   (4,639 )
(10,000 )   Novartis AG (ADR), strike price $57.25, expires 11/16/07   (10,360 )
(10,000 )   Owen & Minor, Inc., strike price $37.50, expires 09/21/07   (20,106 )
(50 )   Pediatrix Medical Group, Inc., strike price $60, expires 11/19/07   (4,750 )
(106,200 )   Pfizer, Inc., strike price $25, expires 10/22/07   (57,114 )
(10,000 )   Poniard Pharmaceuticals, Inc., strike price $10, expires 11/02/07   (114 )
(30 )   Pozen, Inc., strike price $20, expires 12/24/07   (8,850 )
(100 )   Regeneron Pharmaceuticals, Inc., strike price $30, expires 11/19/07   (2,000 )
(11,000 )   Roche Holdings AG, strike price 222 CHF, expires 11/06/07   (49,538 )
(480 )   Schering-Plough Corp., strike price $33.50, expires 11/09/07  
(17,846
)
(20,000 )   Schering-Plough Corp., strike price $35.25, expires 11/16/07   (4,336 )
(40 )   Seattle Genetics, Inc., strike price $10, expires 12/24/07   (4,600 )
(10,000 )   St. Jude Medical, Inc., strike price $46, expires 11/16/07   (18,328 )
(200 )   Stryker Corp., strike price $70, expires 09/24/07   (6,000 )
(10,000 )   Stryker Corp., strike price $71, expires 11/16/07   (8,856 )
(75 )   Teva Pharmaceutical Industries Ltd. (ADR), strike price $45, expires 12/24/07   (15,000 )
(200 )   Thoratec Corp., strike price $22.50, expires 10/22/07   (10,000 )
(10,000 )   Thoratec Corp., strike price $23, expires 11/16/07   (6,519 )
(12,000 )   Tongjitang Chinese Medicines Co. (ADR), strike price $12.50, expires 11/09/07   (9,487 )
(10 )   United Therapeutics Corp., strike price $75, expires 11/19/07   (6,500 )
(10,000 )   UnitedHealth Group, Inc., strike price $60.25, expires 11/16/07   (638 )
(30 )   Varian, Inc., strike price $60, expires 08/20/07   (7,500 )
(30 )   Varian, Inc., strike price $65, expires 08/20/07   (900 )
(25 )   Varian, Inc., strike price $65, expires 11/19/07   (5,375 )
(100 )   Waters Corp., strike price $65, expires 08/20/07   (1,000 )
(200 )   Wright Medical Group, Inc., strike price $25, expires 08/20/07   (16,000 )
(800 )   Wright Medical Group, Inc., strike price $25, expires 11/19/07   (140,000 )
(300 )   Wyeth, strike price $52.50, expires 08/20/07   (6,000 )
(300 )   Wyeth, strike price $52.50, expires 09/24/07   (25,500 )
(200 )   Wyeth, strike price $60, expires 10/22/07   (5,000 )
(23,500 )   Wyeth, strike price $60, expires 11/16/07   (273 )
(12,000 )   Zimmer Holdings, Inc., strike price $90.50, expires 11/16/07   (11,099 )
      Total Outstanding Call Options Written
(premium received $(2,262,954))
  (1,908,030 )
      OUTSTANDING PUT OPTIONS WRITTEN—(0.1)%      
(100 )   Abbott Laboratories, strike price $50, expires 08/20/07   (8,500 )
(100 )   Abbott Laboratories, strike price $55, expires 08/20/07   (39,000 )
(275 )   Aetna, Inc., strike price $49.50, expires 08/10/07   (43,769 )
(100 )   Becton Dickinson & Co., strike price $75, expires 08/20/07   (2,000 )
(200 )   Gilead Sciences, Inc., strike price $36.25, expires 08/20/07   (11,000 )
(200 )   Gilead Sciences, Inc., strike price $37.50, expires 08/20/07   (18,000 )
(240 )   Manor Care, Inc., strike price $60, expires 08/20/07   (14,400 )
(140 )   St. Jude Medical, Inc., strike price $45, expires 08/20/07   (33,600 )
      Total Outstanding Put Options Written      
      (premium received $(116,049))   (170,269 )
      Total Outstanding Options Written      
      (cost $(2,379,003))   (2,078,299 )
Total Investments net of outstanding options written—98.0% $ 204,683,096  
Other assets in excess of liabilities—2.0%   4,267,683  
Net Assets—100.0%
$ 208,950,779  

2


BlackRock Health Sciences Trust (BME) (continued)
(Percentages shown are based on Net Assets)


1      Non-income producing security.
 
2      Security, or a portion thereof, pledged as collateral for outstanding options written.
 
3      Represents current yield as of July 31, 2007.
 
4      Cost for federal income tax purposes is $189,211,705. The net unrealized appreciation on a tax basis is $17,549,690, consisting of $22,387,587 gross unrealized appreciation and $4,837,897 gross unrealized depreciation.

 
KEY TO ABBREVIATIONS
ADR  
  American Depositary Receipt
     CHF  
  Swiss Franc      
EUR  
  Euro
 

3


Item 2 – Controls and Procedures

2(a) –      The registrant’s principal executive and principal financial officers or persons performing similar functions have concluded that the registrant’s disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the “1940 Act”)) are effective as of a date within 90 days of the filing of this report based on the evaluation of these controls and procedures required by Rule 30a-3(b) under the 1940 Act and Rule 13a-15(b) under the Securities and Exchange Act of 1934, as amended.
     
2(b) –   There were no changes in the registrant’s internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act (17 CFR 270.30a-3(d)) that occurred during the registrant’s last fiscal quarter that have materially affected, or are reasonably likely to materially affect, the registrant’s internal control over financial reporting.

Item 3 – Exhibits

Certifications – Attached hereto

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
 
BlackRock Health Sciences Trust
   
By:     
/s/ Donald C. Burke
 
Donald C. Burke,
 
Treasurer of
  BlackRock Health Sciences Trust                         
   
Date:
September 20, 2007

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By:     
/s/ Robert S. Kapito
 
Robert S. Kapito,
 
President (principal executive officer) of
 
BlackRock Health Sciences Trust
   
Date:
September 20, 2007
   
By:
/s/ Donald C. Burke
  Donald C. Burke,
  Treasurer (principal financial officer) of
 
BlackRock Health Sciences Trust                         
   
Date:
September 20, 2007