Edgar Filing: IR BIOSCIENCES HOLDINGS INC

irbio10qsb-08082007.htm

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D. C. 20549

FORM 10-QSB

x Quarterly Report Pursuant to Section 13 or 15(d) of the Securities Exchange

Act of 1934

For the quarterly period ended June 30, 2007

o Transition Report Pursuant to Section 13 or 15(d) of the Securities

Exchange Act of 1934

For the transition period from ___________ to _____________

Commission File Number: 033-05384

IR BIOSCIENCES HOLDINGS, INC.

(Exact name of Registrant as specified in its charter)

Delaware		13-3301899
(State or other jurisdiction of incorporation or organization)		(I.R.S. Employer Identification No.)

4021 N. 75th Street, Suite 201, Scottsdale, Arizona 85251

(Address of principal executive offices) Zip Code

Registrant's telephone number, including area code: (480) 922-3926

__________________________________________________________________________

(Former name, former address and former fiscal year, if changed since last report)

Indicate by check mark whether Registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding twelve months or for such shorter period that the Registrant was required to file such reports, and (2) has been subject to such filing requirements for the past 90 days. Yes x No o

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes o No x

The number of shares outstanding of Registrant's common stock as of August 3, 2007 was 114,322,539.

Transitional Small Business Disclosure Format (check one): Yes o No x

Table of Contents

IR BIOSCIENCES HOLDINGS, INC. AND SUBSIDIARY

Table Of Contents

PART I. Financial Information

	Page
Item 1. Financial Statements
Condensed Consolidated Balance Sheet as of June 30, 2007 (unaudited)	F-1
Condensed Consolidated Statement of Losses for the three and six months ended June 30, 2007 and 2006, and for the period of inception (October 30, 2002) to June 30, 2007 (unaudited)	F-2
Condensed Consolidated Statement of Stockholders' Equity (Deficit) from date of inception (October 30, 2002) to June 30, 2007 (unaudited)	F-3 to F-9
Condensed Consolidated Statements of Cash Flows for the six months ended June 30, 2007 and 2006, and for the period of inception (October 30, 2002) to June 30, 2007 (unaudited)	F-10 to F11
Notes to Consolidated Financial Statements	F-12
Item 2. Management's Discussion and Analysis of Financial Condition or Plan of Operation	3
Item 3. Controls and Procedures	9

PART II Other Information

Item 1. Legal Proceedings	10
Item 2. Unregistered Sale of Equity Securities and Use of Proceeds	10
Item 3. Defaults Upon Senior Securities	10
Item 4. Submission of Matters to a Vote of Securities Holders	10
Item 5. Other Information	10
Item 6. Exhibits	10

Signatures	11

Table of Contents

ITEM 1. FINANCIAL INFORMATION

IR BioSciences Holdings, Inc. and Subsidiary

(A Development Stage Company)

Condensed Consolidated Balance Sheet as of June 30, 2007

(Unaudited)

Assets
Current assets

Cash and cash equivalents	$	1,513,379
Prepaid services and other current assets (Note 1)		48,031
Salary advance (Note 1)		3,975

Total current assets		1,565,385

Deposits and other assets (Note 1)		2,260
Furniture and equipment, net of accumulated depreciation of $18,351 (Note 2)		29,747

Total assets	$	1,597,392

Liabilities and Stockholders' Equity
Current liabilities
Accounts payable and accrued liabilities (Note 4)	$	593,806
Current portion of Notes Payable (Note 5)		50,000

Total current liabilities		643,806

Commitments and Contingencies		-

Stockholders' Equity
Preferred stock, $0.001 par value:
10,000,000 shares authorized, no shares issued and outstanding		-
Common stock, $0.001 par value; 250,000,000 shares authorized;
114,322,539 shares issued and outstanding at June 30, 2007 (Note 6)		114,323
Additional paid-in capital		16,100,898
Deficit accumulated during the development stage		(15,261,635	)
Total stockholders’ equity		953,586

Total liabilities and stockholders' equity	$	1,597,392

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements.

F-1

Table of Contents

IR BioSciences Holdings, Inc. and Subsidiary

(A Development Stage Company)

Condensed Consolidated Statement of Losses

For the three and six months ended June 30, 2007 and 2006,

And for the period of inception (October 30, 2002) to June 30, 2007

(Unaudited)

	For the Three Months Ended June 30,						For the Six Months Ended June 30,						For the Period October 30, 2002 to
		2007			2006			2007			2006		June 30, 2007
Revenues	$	-		$	-		$	-		$	-		$	-

Operating expenses:

Selling, general and administrative expenses		1,141,908			601,972			2,016,018			1,163,116			12,585,636
Merger fees and costs		-			-			-			-			350,000
Financing cost		-			-			-			-			90,000
Impairment of intangible asset costs		-			-			-			-			6,393
Total operating expenses		1,141,908			601,972			2,016,018			1,163,116			13,032,029

Operating loss		(1,141,908	)		(601,972	)		(2,016,018	)		(1,163,116	)		(13,032,029	)

Other expense:
Cost of penalty for late registration of shares		-			(994,574	)		-			(438,601	)		2,192,160
(Gain) loss from marking to market - warrant portion
of penalty for late registration of shares		-			(39,887	)		-			(46,755	)		(378,198	)
(Gain) loss from marketing to market - stock portion
of penalty for late registration of shares		-			(124,524	)		-			(72,101	)		(760,058	)
Interest (income) expense, net		(26,812	)		15,057			(47,678	)		14,891			1,167,587

Total other (income) expense		(26,812	)		(1,143,928	)		(47,678	)		(542,566	)		2,221,491

Income (loss) before income taxes		(1,115,096	)		541,956			(1,968,340	)		(620,550	)		(15,253,520	)

Provision for income taxes		-			-			(8,115	)		-			(8,115	)

Net (loss)	$	(1,115,096	)	$	541,956		$	(1,976,455	)	$	(620,550	)	$	(15,261,635	)

Net income (loss) per share - basic and diluted	$	(0.01	)	$	0.01		$	(0.02	)	$	(0.01	)	$	(0.28	)

Weighted average shares outstanding -
basic and diluted		114,322,539			69,632,567			114,119,683			69,554,432			54,267,855

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements.

F-2

Table of Contents

IR BioSciences Holding, Inc. and Subsidiary

(A Development Stage Company)

Consolidated Statement of Stockholders' Equity (Deficit)

From date of inception (October 30, 2002) to June 30, 2007

(Unaudited)

					Additional						Common
	Common Stock				Paid-In			Deferred			Stock		Accumulated
	Shares		Amount		Capital			Compensation			Subscribed		Deficit			Total
Balance at October 30, 2002 (date of inception)		-	$	-	$	-		$	-		$	-	$	-		$	-

Shares of common stock issued at $0.0006 per share to founders for license of proprietary right in December 2002		16,612,276		16,612		(7,362	)		-			-		-			9,250

Shares of common stock issued at $0.0006 per share to founders for services rendered in December 2002		1,405,310		1,405		(623	)		-			-		-			782

Shares of common stock issued at $0.1671 per share to consultants for services rendered in December 2002		53,878		54		8,946			(9,000	)		-		-			-

Sale of common stock for cash at $0.1671 per share in December 2002		185,578		186		30,815			-			-		-			31,001

Net loss for the period from inception (October 30, 2002) to December 31, 2002		-		-		-			-			-		(45,918	)		(45,918	)

Balance at December 31, 2002 (reflective of stock splits)		18,257,042	$	18,257	$	31,776		$	(9,000	)	$	-	$	(45,918	)	$	(4,885	)

F-3

Table of Contents

IR BioSciences Holding, Inc. and Subsidiary

(A Development Stage Company)

Consolidated Statement of Stockholders' Equity (Deficit)

From date of inception (October 30, 2002) to June 30, 2007

(Unaudited)

(Continued)

Additional

Common

Common Stock

Paid-In

Deferred

Stock

Accumulated

Shares

Amount

Capital

Compensation

Subscribed

Deficit

Total


Shares granted to consultants at $0.1392 per share for services rendered in January 2003	98,776		99		13,651			-		-		-			13,750

Sale of shares of common stock for cash at $0.1517 per share in January 2003	329,552		330		49,670			-		-		-			50,000

Shares granted to consultants at $0.1392 per share for services rendered in March 2003	154,450		154		21,346			-		-		-			21,500

Conversion of notes payable to common stock at $0.1392 per share in April 2003	1,436,736		1,437		198,563			-		-		-			200,000

Shares granted to consultants at $0.1413 per share for services rendered in April 2003	14,368		14		2,016			-		-		-			2,030

Sale of shares of common stock for cash at $0.2784 per share in May 2003	17,960		18		4,982			-		-		-			5,000

Sales of shares of common stock for cash at $0.2784 per share in June 2003	35,918		36		9,964			-		-		-			10,000

Conversion of notes payable to common stock at $0.1392 per share in June 2003	718,368		718		99,282			-		-		-			100,000

Beneficial conversion feature associated with notes issued in June 2003	-		-		60,560			-		-		-			60,560

Amortization of deferred compensation	-		-		-			9,000		-		-			9,000

Costs of GPN Merger in July 2003	2,368,130		2,368		(123,168	)		-		-		-			(120,799	)

Value of warrants issued with extended notes payable in October 2003	-		-		189,937			-		-		-			189,937

Value of Company warrants issued in conjunction with fourth quarter notes payable issued October through December 2003	-		-		207,457			-		-		-			207,457

Value of warrants contributed by founders in conjunction with fourth quarter notes payable issued October through December 2003	-		-		183,543			-		-		-			183,543

Value of warrants issued for services in October through December 2003	-		-		85,861			-		-		-			85,861

Net loss for the twelve month period ended December 31, 2003	-		-		-			-		-		(1,856,702	)		(1,856,702	)

Balance at December 31, 2003	23,431,300	$	23,431	$	1,035,441		$	-	$	-	$	(1,902,620	)	$	(843,748	)

F-4

Table of Contents

IR BioSciences Holding, Inc. and Subsidiary

(A Development Stage Company)

Consolidated Statement of Stockholders' Equity (Deficit)

From date of inception (October 30, 2002) to June 30, 2007

(Unaudited)

(Continued)

Additional

Common

Common Stock

Paid-In

Deferred

Stock

Accumulated

Shares

Amount

Capital

Compensation

Subscribed

Deficit

Total


Shares granted at $1.00 per share pursuant to the Senior Note Agreement in January 2004	600,000	600	599,400	(600,000	)	-	-	-

Shares issued at $1.00 per share to a consultant for services rendered in January 2004	800,000	800	799,200	(800,000	)	-	-	-

Shares issued to a consultant at $0.62 per share for services rendered in February 2004	40,000	40	24,760	(24,800	)	-	-	-

Shares issued to a consultant at $0.40 per share for services rendered in March 2004	1,051,600	1,051	419,589	(420,640	)	-	-	-

Shares issued to a consultant at $0.50 per share for services rendered in March 2004	500,000	500	249,500	(250,000	)	-	-	-

Shares sold for cash at $0.15 per share in March, 2004	8,000	8	1,192	-		-	-	1,200

Shares issued at $0.50 per share to consultants for services rendered in March 2004	20,000	20	9,980	-		-	-	10,000

Shares issued to a consultant at $0.40 per share for services rendered in March 2004	2,000	2	798	-		-	-	800

Shares issued to consultants at $0.32 per share for services rendered in March 2004	91,600	92	29,220	-		-	-	29,312

Shares to be issued to consultant at $0.41 per share in April 2004 for services to be rendered through March 2005	-	-	-	(82,000	)	-	-	(82,000	)

Shares granted pursuant to the New Senior Note Agreement in April 2004	600,000	600	149,400	(150,000	)	-	-	-

F-5

Table of Contents

IR BioSciences Holding, Inc. and Subsidiary

(A Development Stage Company)

Consolidated Statement of Stockholders' Equity (Deficit)

From date of inception (October 30, 2002) to June 30, 2007

(Unaudited)

(Continued)

Additional

Common

Common Stock

Paid-In

Deferred

Stock

Accumulated

Shares

Amount

Capital

Compensation

Subscribed

Deficit

Total


Shares issued to officer at $0.32 per share for services rendered in April 2004	200,000	200	63,800	-		-	-	64,000

Conversion of Note Payable to common stock at $0.10 per share in May 2004	350,000	350	34,650	-		-	-	35,000

Beneficial Conversion Feature associated with note payable in May 2004	-	-	35,000	-		-	-	35,000

Issuance of warrants to officers and founder for services rendered in May 2004	-	-	269,208	-		-	-	269,208

Shares to a consultant at $0.20 per share as a due diligence fee in May 2004	125,000	125	24,875	-		-	-	25,000

Shares issued to a consultant at $1.00 per share for services to be rendered over twelve months beginning May 2004	500,000	500	499,500	(500,000	)	-	-	-

Beneficial Conversion Feature associated with notes payable issued in June 2004	-	-	3,000	-		-	-	3,000

Issuance of warrants to note holders in April, May, and June 2004	-	-	17,915	-		-	-	17,915

Issuance of warrants to employees and consultants for services rendered in April through June 2004	-	-	8,318	-		-	-	8,318

Shares issued in July to a consultant at $0.10 for services to be rendered through July 2005	250,000	250	24,750	(25,000	)	-	-	-

Shares issued to a consultant in July and September at $0.41 per share for services to be rendered through April 2005	200,000	200	81,800	-		-	-	82,000

Shares issued to a consultant in September at $0.12 to $0.22 for services rendered through September 2004	127,276	127	16,782	-		-	-	16,909

Shares issued in July to September 2004 as interest on note payable	300,000	300	35,700	-		-	-	36,000

Issuance of warrants with notes payable in July and August 2004	-	-	72,252	-		-	-	72,252

Accrued deferred compensation in August 2004 to a consultant for 100,000 shares at $0.10 per share, committed but unissued	-	-	-	(10,000	)	-	-	(10,000	)

Shares issued in August 2004 at $0.14 to a consultant for services to be performed through October 2004	100,000	100	13,900	(14,000	)	-	-	-

F-6

Table of Contents

IR BioSciences Holding, Inc. and Subsidiary

(A Development Stage Company)

Consolidated Statement of Stockholders' Equity (Deficit)

From date of inception (October 30, 2002) to June 30, 2007

(Unaudited)

(Continued)

Additional

Common

Common Stock

Paid-In

Deferred

Stock

Accumulated

Shares

Amount

Capital

Compensation

Subscribed

Deficit

Total

Shares issued in August 2004 at $0.125 per share for conversion of $30,000 demand loan	240,000			240			29,760			-			-		-			30,000

Shares issued in August 2004 at $0.16 per share to a consultant for services provided.	125,000			125			19,875			-			-		-			20,000

Shares issued in October 2004 to employees at $0.16 to $0.25 per share	48,804			49			8,335			-			-		-			8,384

Commitment to issue 100,000 shares of stock to a consultant at $0.23 per share for services to be provided through September 2005	-			-			-			(23,000	)		-		-			(23,000	)

Sale of stock for cash in October at $0.125 per share, net of costs of $298,155	18,160,000			18,160			1,345,763			-			-		-			1,363,923

Value of warrants issued with sale of common stock in October, net of costs	-			-			607,922			-			-		-			607,922

Issuance of warrant to officer in October, 2004	-			-			112,697			-			-		-			112,697

Issuance of stock to investment bankers in October 2004 for commissions earned	4,900,000			4,900			(4,900	)		-			-		-			-

Conversion of accounts payable to stock in October at $0.125 per share	1,257,746			1,258			107,382			-			-		-			108,640

Value of warrants issued with accounts payable conversions	-			-			48,579			-			-		-			48,579

Conversion of demand loan to stock in October at $0.11 per share	93,300			93			10,170			-			-		-			10,263

Forgiveness of notes payable in October 2004	-			-			36,785			-			-		-			36,785

Issuance of stock to officer and director at $0.125 per share in October for conversion of liability	1,440,000			1,440			122,493			-			-		-			123,933

Value of warrants issued with officer and director conversion of liabilities	-			-			56,067			-			-		-			56,067

Conversion of debt and accrued interest to common stock at $0.075 to $0.125 per share	6,703,151			6,703			417,514			-			-		-			424,217

Value of warrants issued with conversion of debt	-			-			191,111			-			-		-			191,111

Conversion of note payable in October into common stock at $0.075 per share	67,616			68			4,932			-			-		-			5,000

Issuance of warrants to note holders in October 2004	-			-			112,562			-			-		-			112,562

Value of shares issued to CFO as compensation	100,000			100			34,900			-			-		-			35,000

Value of warrants issued to members of advisory committees in November and December	-			-			16,348			-			-		-			16,348

Beneficial conversion feature associated with notes payable	-			-			124,709			-			-		-			124,709

Shares issued per conversion of Note Payable - correction	(9,002	)		(9	)		9			-			-		-			-

Amortization of deferred compensation through December 31, 2004	-			-			-			2,729,454			-		-			2,729,454

Loss for the twelve months ended December 31, 2004	-			-			-			-			-		(5,305,407	)		(5,305,407	)

Balance at December 31, 2004	62,423,391		$	62,423		$	7,922,943		$	(169,986	)	$	-	$	(7,208,027	)	$	607,353

F-7

Table of Contents

IR BioSciences Holding, Inc. and Subsidiary

(A Development Stage Company)

Consolidated Statement of Stockholders' Equity (Deficit)

From date of inception (October 30, 2002) to June 30, 2007

(Unaudited)

(Continued)

Additional

Common

Common Stock

Paid-In

Deferred

Stock

Accumulated

Shares

Amount

Capital

Compensation

Subscribed

Deficit

Total


Sale of shares of common stock for cash at $0.20 per share in March 2005 for warrant exercise, net of costs	6,600,778		6,600		1,184,256		-			-		-			1,190,856

Value of warrants issued to members of advisory committees in March 2005	-		-		137,049		-			-		-			137,049

Deferred compensation in February 2005 to a consultant for 50,000 shares of common stock at $0.65 per share.	-		-		-		(32,500	)		-		-			(32,500	)

Warrants exercised at $0.05 per share in June 2003	80,000		80		3,920		-			-		-			4,000

Value of warrants issued to members of advisory committee in June 2005	-		-		70,781		-			-		-			70,781

Value of warrants issued to investors and service providers in June 2005	-		-		32,991		-			-		-			32,991

Issuance of 232,153 shares of common stock in July 2005 for conversion of notes payable	232,153		232		64,771		-			-		-			65,003

Issuance of 100,000 shares of common stock in August 2005 to a consultant for services provided	100,000		100		9,900		-			-		-			10,000

Value of warrants issued to advisory committee in September 2005 for services	-		-		20,491		-			-		-			20,491

Amortization of deferred comp for the twelve months ended December, 2005	-		-		-		199,726			-		-			199,726

Value of warrants issued in October and December 2005 to investors and service providers	-		-		18,399		-			-		-			18,399

Loss for the year ended December 31,2005										-		(4,591,107	)		(4,591,107	)

Balance at December 31, 2005	69,436,322	$	69,435	$	9,465,501	$	(2,760	)	$	-	$	(11,799,134	)	$	(2,266,958	)

F-8

Table of Contents

IR BioSciences Holding, Inc. and Subsidiary

(A Development Stage Company)

Consolidated Statement of Stockholders' Equity (Deficit)

From date of inception (October 30, 2002) to June 30, 2007

(Unaudited)

(Continued)

Additional

Common

Common Stock

Paid-In

Deferred

Stock

Accumulated

Shares

Amount

Capital

Compensation

Subscribed

Deficit

Total


Issuance of 100,000 shares to officer, previously accrued	100,000		100		41,316			-		-			-			41,416

Value of warrants issued to members of advisory committee in March 2006	-		-		8,399			-		-			-			8,399

Amortization of deferred compensation for the three months ended March 31, 2006	-		-		-			2,760		-			-			2,760

Issuance of common stock in May 2006 to a consultant for services provided	34,464		35		16,162			-		-			-			16,197

Conversion of accrued interest to common stock at $0.125 per share in May, 2006	19,288		19		2,392			-		-			-			2,411

Conversion of accrued interest to common stock at $0.125 per share in May, 2006	16,324		16		2,025			-		-			-			2,041

Conversion of accrued interest to common stock at $0.10 per share in May, 2006	13,454		14		1,341			-		-			-			1,355

Common stock issued pursuant to the exercise of warrants at $0.09 per share in June 2006	5,000		5		445			-		-			-			450

Value of warrants issued to members of advisory committee in June 2006	-		-		8,820			-		-			-			8,820

Value of warrants issued to members of advisory committee in September 2006	-		-		3,495			-		-			-			3,495

Value of warrants issued to officers	-		-		50,874			-		-			-			50,874

Issuance of penalty Common Stock, previously accrued	4,150,798		4,151		867,514			-		-			-			871,665

Issuance of penalty warrants, previously accrued	-		-		182,239			-		-			-			182,239

Value of options issued to officer	-		-		78,802			-		-			-			78,802

Value of warrants issued to members of advisory committee in December 2006	-		-		1,974			-		-			-			1,974

Issuance of Common Stock for cash	34,266,250		34,267		4,579,282			-		-			-			4,613,549

Common stock to be issued as commission for equity fund raising	-		-		(5,483	)		-		5,483			-			-

Value of options issued to officer	-		-		32,120			-		-			-			32,120

Value of options issued to officer	-		-		185,472			-		-			-			185,472

Loss for the year ended December 31, 2006	-		-		-			-		-			(1,486,046	)		(1,486,046	)

Balance at December 31, 2006	108,041,900	$	108,042	$	15,522,690		$	-	$	5,483		$	(13,285,180	)	$	2,351,035

Common stock issued as commission for equity fund raising	5,482,600		5,483		-			-		(5,483	)		-			-

Common stock issued to consultant in January, 2007 at $0.15 per share	298,039		298		44,408			-		-			-			44,706

Common stock issued to consultants in January, 2007 at $0.155 per share	400,000		400		61,600			-		-			-			62,000

Common stock issued to consultants in January, 2007 at $0.15 per share	100,000		100		14,900			-		-			-			15,000

Value of options issued to officer in January, February and March 2007	-		-		181,440			-		-			-			181,440

Value of options issued to employee in January, 2007	-		-		1,302			-		-			-			1,302

Loss for the three months ended March 31, 2007	-		-		-			-		-			(861,359	)		(861,359	)

Balance at March 31, 2007	114,322,539	$	114,323	$	15,826,340		$	-	$	-		$	(14,146,539	)	$	1,794,124

Value of options issued to officer in January, February and March 2007	-		-		183,456			-		-			-			183,456

Value of options issued to employee in January 2007	-		-		1,302			-		-			-			1,302

Value of warrants issued to consultant in April 2007	-		-		89,800			-		-			-			89,800

Loss for the three months ended June 30, 2007	-		-		-			-		-			(1,115,096	)		(1,115,096	)

Balance at June 30, 2007	114,322,539	$	114,323	$	16,100,898		$	-	$	-		$	(15,261,635	)	$	953,586

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements

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IR BioSciences Holdings, Inc. and Subsidiary

(A Development Stage Company)

Condensed Consolidated Statements of Cash Flows

For the Six Months Ended June 30, 2007 and 2006,

And For the Period of Inception (October 30, 2002) to June 30, 2007

(Unaudited)

	For the Six Months Ended June 30,						For the Period October 30, 2002 to
	2007			2006			June 30, 2007
Cash flows from operating activities:
Net loss	$	(1,976,455	)	$	(620,550	)	$	(15,261,635	)
Adjustments to reconcile net loss to net
cash used in operating activities:
Non-cash compensation		564,168			45,926			4,883,684
Cost of penalty for late registration of shares - stock portion		-			(360,197	)		1,631,726
Cost of penalty for late registration of shares - warrant portion		-			(78,404	)		560,434
(Gain) loss from marking to market - stock portion of penalty
for late registration of shares		-			(72,101	)		(760,058	)
(Gain) loss from marking to market - warrant portion of penalty
for late registration of shares		-			(46,755	)		(378,198	)
Legal fees for note payable		-			10,125			20,125
Placement fees for note payable		-			40,000			65,000
Impairment of intangible asset		-			-			6,393
Interest expense		-			-			156,407
Amortization of discount on notes payable		-			-			1,006,935
Depreciation and amortization		6,109			3,882			43,708
Changes in operating assets and liabilities:
Prepaid services and other assets		-			17,137			(35,158	)
Accounts payable and accrued expenses		177,543			324,890			839,560
Salary advance		(2,475	)		-			(3,975	)

Net cash used in operating activities		(1,231,110	)		(736,047	)		(7,225,052	)

Cash flows from investing activities:
Acquisition of property and equipment		(7,614	)		(16,475	)		(48,098	)

Net cash used in investing activities		(7,614	)		(16,475	)		(48,098	)

Cash flows from financing activities:
Proceeds from notes payable and cash advances		-			509,875			1,953,375
Principal payments on notes payable and demand loans		-			-			(1,044,747	)
Shares of stock sold for cash		-			-			7,873,451
Proceeds from exercise of warrant		-			450			4,450
Officer repayment of amounts paid on his behalf		-			-			19,880
Cash paid on behalf of officer		-			-			(19,880	)

Net cash provided by financing activities		-			510,325			8,786,529

Net increase (decrease) in cash and cash equivalents		(1,238,724	)		(242,197	)		1,513,379

Cash and cash equivalents at beginning of period		2,752,103			265,860			-

Cash and cash equivalents at end of period	$	1,513,379		$	23,663		$	1,513,379

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IR BioSciences Holdings, Inc. and Subsidiary

(A Development Stage Company)

Condensed Consolidated Statements of Cash Flows

For the Six Months Ended June 30, 2007 and 2006,

And For the Period of Inception (October 30, 2002) to June 30, 2007

(Unaudited)

(Continued)

	For the Six Months Ended June 30,						For the Period October 30, 2002 to
	2007			2006			June 30, 2007


Supplemental disclosures of cash flow information:

Cash paid during the period for:
Interest	$	-	$	438		$	80,053

Taxes	$	-	$	-		$	8,115

Acquisition and capital restructure:
Assets acquired		-		-			-
Liabilities assumed		-		-			(120,799	)
Common stock retained		-		-			(2,369	)
Adjustment to additional paid-in capital		-		-			123,168
Organization costs		-		-			350,000
Total consideration paid	$	-	$	-		$	350,000.00

Common stock issued in exchange for proprietary rights	$	-	$	-		$	9,250

Common stock issued in exchange for services	$	77,000	$	16,198		$	3,018,483

Common stock issued in exchange for previously incurred debt and accrued interest	$	-	$	5,807		$	1,066,401

Common stock issued in exchange as interest	$	-	$	-		$	36,000

Amortization of beneficial conversion feature	$	-	$	-		$	223,269

Stock options and warrants issued in exchange for services rendered	$	457,300	$	-		$	1,576,949

Debt and accrued interest forgiveness from note holders	$	-	$	-		$	36,785

Common stock issued in satisfaction of amounts due to an Officer and a Director	$	-	$	-		$	180,000

Common stock issued in satisfaction of accounts payable	$	-	$	-		$	157,219

Deferred compensation to a consultant accrued in March 2005	$	-	$	-		$	2,630,761

Amortization of deferred compensation	$	-	$	2,760		$	202,486

Fair value of common stock and warrants in payable in connection with late filing of registration statement	$	-	$	(994,574	)	$	3,684,664

Gain from marking to market - stock portion of penalty for late registration of shares	$	-	$	(124,524	)	$	(1,124,255	)

Gain from marking to market - warrant portion of penalty for late registration of shares	$	-	$	(39,887	)	$	(456,603	)

Impairment of intangible asset	$	-	$	-		$	6,393

Issuance of stock to Officer, previously accrued	$	-	$	41,416		$	41,416

Value of warrants issued to members of advisory board	$	-	$	17,219		$	22,688

Services for note payable	$	-	$	9,750		$	9,750

Issuance of shares for accounts payable	$	44,706	$	-		$	44,706

Stock issued as commission for equity fund raising	$	5,483	$	-		$	5,483

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements

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IR BIOSCIENCES HOLDINGS, INC.

(A DEVELOPMENT STAGE COMPANY)

NOTES TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

June 30, 2007

(Unaudited)

Note 1 - Summary Of Accounting Policies

General

The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with the instructions to Form 10-QSB, and therefore, do not include all the information necessary for a fair presentation of financial position, results of operations and cash flows in conformity with accounting principles generally accepted in the United States of America for a complete set of financial statements.

In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. The results from operations for the three and six-month period ended June 30, 2007 are not necessarily indicative of the results that may be expected for the year ended December 31, 2007. The unaudited condensed consolidated financial statements should be read in conjunction with the December 31, 2006 financial statements and footnotes thereto included in the Company's annual report on SEC Form 10-KSB filed with the Securities and Exchange Commission on April 17, 2007 and Form 10-KSB/A filed with the Securities and Exchange Commission on April 30, 2007 and on May 8, 2007.

Business and basis of presentation

IR BioSciences Holdings, Inc. (the "Company," "we," or "us") formerly GPN Network, Inc. ("GPN") is currently a development stage company under the provisions of Statement of Financial Accounting Standards ("SFAS") No. 7. The Company, which was incorporated under the laws of the State of Delaware on October 30, 2002, is a development-stage biopharmaceutical company. Through our wholly owned subsidiary, ImmuneRegen BioSciences, Inc., the Company is engaged in the research and development of potential drugs. The Company’s goal is to develop therapeutics to be used for the protection of the body from exposure to harmful agents such as toxic chemicals and radiation, as well as, biological agents, including influenza and anthrax. The Company’s research and development efforts are at a very early stage and Radilex and Viprovex , the Company’s potential drug candidates, have only undergone pre-clinical testing in mice. From its inception through the date of these financial statements, the Company has recognized no revenues and has incurred significant operating expenses.

The consolidated financial statements include the accounts of the Company and its wholly owned subsidiary, ImmuneRegen BioSciences, Inc. Significant inter-company transactions have been eliminated in consolidation.

Reclassification

Certain reclassifications have been made to conform to prior periods' data to the current presentation. These reclassifications had no effect on reported losses.

Stock based compensation

Effective January 1, 2006, the Company adopted SFAS No. 123 (revised), "Share-Based Payment" (SFAS 123(R)) utilizing the modified prospective approach. Prior to the adoption of SFAS 123(R) we accounted for stock option grant in accordance with APB Opinion No. 25, "Accounting for Stock Issued to Employees" (the intrinsic value method), and accordingly, recognized compensation expense for stock option grants.

Under the modified prospective approach, SFAS 123(R) applies to new awards and to awards that were outstanding on January 1, 2006 that are subsequently modified, repurchased or cancelled. Under the modified prospective approach, compensation cost recognized in the nine months of fiscal 2006 includes compensation cost for all share-based payments granted prior to, but not yet vested as of January 1, 2006, based on the grant-date fair value estimated in accordance with the original provisions of SFAS 123, and compensation cost for all share-based payments granted subsequent to January 1, 2006 based on the grant-date fair value estimated in accordance with the provisions of SFAS 123(R). Prior periods were not restated to reflect the impact of adopting the new standard.

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A summary of option activity under the Plan as of June 30, 2007, and changes during the period ended are presented below:

	Options		Weighted Average Exercise Price
Outstanding at December 31, 2006		5,914,212	$	0.50
Issued		100,000		0.13
Exercised		-		-
Forfeited or expired		-		-
Outstanding at June 30, 2007		6,014,212	$	0.49

Non-vested at June 30, 2007		518,270	$	0.21
Exercisable at June 30, 2007		5,495,942	$	0.52

Aggregate intrinsic value of options outstanding and exercisable at June 30, 2007 was $0. Aggregate intrinsic value represents the difference between the Company's closing stock price on the last trading day of the fiscal period, which was $0.17 as of June 29, 2007, and the exercise price multiplied by the number of options outstanding. As of June 30, 2007, total unrecognized stock-based compensation expense related to stock options was $114,809. The total fair value of options vested during the six months ended June 30, 2007 was $367,501.

Interim financial statements

The accompanying balance sheet as of June 30, 2007, the statements of operations for the three and six months ended June 30, 2007 and 2006, and for the period of inception (October 30, 2002) to June 30, 2007, and the statements of cash flows for six months ended June 30, 2007 and 2006, and from the period of inception (October 30, 2002) to June 30, 2007 are unaudited. These unaudited interim financial statements include all adjustments (consisting of normal recurring accruals), which, in the opinion of management, are necessary for a fair presentation of the results of operations for the periods presented. Interim results are not necessarily indicative of the results to be expected for a full year.

Use of estimates

The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reported periods. Actual results could materially differ from those estimates.

Long-lived assets

The Company accounts for its long-lived assets under the provision of Statements of Financial Accounting Standards No. 121, "Accounting for the Impairment of Long-Lived Assets and for Long-Lived Assets To Be Disposed Of." The Company's long-lived assets are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of such assets may not be recoverable. Events relating to recoverability may include significant unfavorable changes in business conditions, recurring losses, or a forecasted Inability to achieve break-even operating results over an extended period. The Company evaluates the recoverability of long-lived assets based upon forecasted undiscounted cash flows. Should an impairment in value be indicated, the carrying value of intangible assets will be adjusted, based on estimates of future discounted cash flows resulting from the use and ultimate disposition of the asset.

Prepaid services and other current assets

Prepaid services and other current assets at June 30, 2007 consist of the following:

Prepaid insurance	$	12,434
Prepaid expenses		35,597
	$	48,031

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Salary Advance

The Company has made an advance of salary to one employee in the amount of $3,975 as of June 30, 2007.

Deposits and other assets

Deposits and other assets consist of a deposit on leased office space in the amount of $2,260 as of June 30, 2007.

Note 2 – Furniture and equipment

Furniture and equipment are valued at cost. Depreciation and amortization are provided over the estimated useful lives up to seven years using the straight-line method. The estimated service lives of property and equipment are as follows:

Computer equipment	3 years
Laboratory equipment	3 years
Furniture	7 years

Depreciation expense for the three months ended June 30, 2007 and 2006 was $3,130 and $1,941, respectively. The amount depreciated from the date of inception (October 30, 2002) through June 30, 2007 was $18,351.

The Company’s furniture and equipment at June 30, 2007 consists of the following:

Office Equipment	$	41,950
Office furniture and fixtures		6,148
		48,098
Accumulated depreciation		(18,351	)
Total	$	29,747

Note 3 - Related Party Transactions

Credit Cards

The Company has a line of credit with Bank of America for $25,000. Our Chief Executive Officer Michael Wilhelm co-signs this line of credit. At month-end June 30, 2007 the Company had an outstanding balance on the line of credit of $15,847.

Options

During the three months ended June 30, 2007, options to purchase a total of 798,113 shares at prices of $0.22 to $0.231 per share were vested. These options are held by the Company’s President and Chief Executive Officer. The Company charged the amount of $183,456 to operations during the three months ended June 30, 2007.

Note 4 - Accounts Payable And Accrued Liabilities

Accounts payable and accrued liabilities consisted of the following at June 30, 2007:

Accounts payable and accrued liabilities	$	526,041
Accounts payable - shell company		34,926
Credit cards payable		15,845
Insurance notes payable		5,138
Interest payable		8,656
State income tax payable		3,200
	$	593,806

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Note 5 - Notes Payable

In August 2006, the cash advance in the amount of $50,000 the Company received from a director was converted into a promissory note payable. This note bears interest at the rate of 12% per annum. During the three months ended June 30, 2007, the Company accrued interest in the amount of $1,496 on this note.

Note 6 - Equity

Common stock

In January 2007, the Company issued 5,482,600 shares of common stock as commission for the Company’s equity financing completed during the year ended December 31, 2006. These shares were shown as common stock subscribed on the Company’s balance sheet at December 31, 2006.

In January 2007, the Company issued 298,039 shares of common stock at a price of $0.15 per share to an employee in satisfaction of a liability previously accrued.

In January 2007, the Company issued 400,000 shares of common stock at a price of $0.155 per share to a consultant for services to be performed through June 2007. The Company charged the amount of $62,000 to prepaid services during the three months ended June 30, 2007.

In January 2007, the Company issued 100,000 shares of common stock at a price of $0.15 per share to a consultant for services to be performed through March 2007. The Company charged the amount of $15,000 to operations during the three months ended June 30, 2007.

Warrants

The following table summarizes the changes in warrants outstanding and the related prices for the shares of the Company's common stock issued to non-employees of the Company. These warrants were granted in lieu of cash compensation for services performed or financing expenses and in connection with placement of convertible debentures.

Warrants Outstanding			Warrants Exercisable
		Weighted			Weighted
		Average	Weighted		Average
		Remaining	Average		Remaining
Exercise	Number	Contractual	Exercise	Number	Contractual
Prices	Outstanding	Life (years)	Price	Exercisable	Life (years)
$ .05-.10	594,780	1.91	$.05-.10	594,780	1.91
.125-.22	2,514,319	3.55	.125-.22	1,764,319	3.01
.23-.56	31,477,434	3.72	.23-.56	27,977,430	3.58
1.00	677,564	1.44	1.00	677,564	1.44
2.00	16,550	1.13	2.00	16,550	1.13
	35,280,647	3.63		31,030,643	3.46

Transactions involving warrants are summarized as follows:

	Number of Shares (post-split)			Weighted Average Price Per Share (post-split)
Outstanding at December 31, 2006		30,651,543		$	0.37
Granted		5,000,000			0.28
Exercised		-			-
Cancelled or expired		(370,900	)		0.32
Outstanding at June 30, 2007		35,280,647		$	0.35

The estimated value of the compensatory warrants granted to non-employees in exchange for services and financing expenses was determined using the Black-Scholes pricing model and the following assumptions:

	2007	2006
Significant assumptions (weighted-average):
Risk-free interest rate at grant date	4.75%	4.50% to 4.75%
Expected stock price volatility	87.71%	93% to 73%
Expected dividend payout	-	-
Expected option life-years (a)	3 to 5	3 to 5

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Options

In January 2007, the Company issued options to purchase 100,000 shares of common stock an employee. The options vest 12,500 every quarter for the next two years. The Company charged to operations the amount of $1,302 the value of the options that vested during the three months ended June 30, 2007.

On April 24, 2007, the Board of Directors of the Company appointed a new director, Robert J. Hariri, M.D., Ph.D., to the Company's Board of Directors to fill a vacant directorship. Subject to the Board’s approval, for his service as a member of the Company’s Board of Directors, the Company will grant to Dr. Hariri under the Company’s 2003 Stock Option, Deferred Stock and Restricted Stock Plan, a non-qualified stock option to purchase 1,000,000 shares of common stock at an exercise price per share equal to 85% of the fair market value on the date of the grant approval to vest within 30 days. As of June 30, 2007, the Board has not approved the non-qualified stock issuance.

On May 14, 2007, the Board of Directors of the Company appointed a new director, Lance K. Gordon, Ph.D., to the Company's Board of Directors to fill a vacant directorship. Subject to the Board’s approval, for his service as a member of the Company’s Board of Directors, the Company will grant to Dr. Gordon under the Company’s 2003 Stock Option, Deferred Stock and Restricted Stock Plan, a non-qualified stock option to purchase 1,000,000 shares of common stock at an exercise price per share equal to 85% of the fair market value on the date of the grant approval to vest within 30 days. As of June 30, 2007, the Board has not approved the non-qualified stock issuance.

During the six months ended June 30, 2007, options to purchase a total of 798,113 shares of common stock held by the Company’s president and chief executive officer were vested. The Company charged to operations the amount of $183,456 for the value of the options during the six months ended June 30, 2007.

The following table summarizes the changes in options outstanding and the related prices for the shares of the Company's common stock issued to employees of the Company under a non-qualified employee stock option plan.

	Options Outstanding					Options Exercisable
Exercise Prices		Number Outstanding		Weighted Average Remaining Contractual Life (years)		Weighted Average Exercise Price		Number Exercisable		Weighted Average Remaining Contractual Life (years)
$	0.128-0.22		3,800,000		4.22	$	0.128-0.22		3,329,668		4.82
	0.23		1,896,970		4.04		0.23		1,849,032		4.15
	0.31		1,000		3.46		0.31		1,000		3.46
	0.33		103,030		3.14		0.33		103,030		3.14
	0.44		150,000		3.01		0.44		150,000		3.01
	25.00		63,212		2.75		25.00		63,212		2.75
			6,014,212						5,495,942

Options not vested are not exercisable.

Transactions involving stock options issued to employees are summarized as follows:

	Number of Shares		Weighted Average Price Per Share
Outstanding at December 31, 2006		5,914,212	$	0.50
Granted		100,000		0.13
Exercised		-		-
Expired		-		-
Outstanding at June 30, 2007		6,014,212	$	0.49

Non-vested at June 30, 2007		518,270	$	0.21
Exercisable June 30, 2007		5,495,942	$	0.52

Note 7 - Subsequent Events

Effective August 1, 2006, we converted a cash advance from a director into a twelve-month unsecured senior promissory note in the amount of $50,000 bearing an annual interest rate of 12%. We repaid $56,000, the outstanding principal amount of the note plus accrued interest in the amount of $6,000, on August 6, 2007.

On August 1, 2007 the Board of Directors approved by Unanimous Written Consent to grant stock option awards totaling ten million stock options to officers, directors and consultants pursuant to the terms of the 2003 Stock Option, Deferred Stock and Restricted Stock Plan. The awards are as follows: Six million sixty-thousand (6,060,000) stock options were issued to Officers and employees in the form of incentive stock options with a strike price of $0.195 per share and non-qualified stock options with a strike price equal to $0.166 per share; three million two-hundred fifty-thousand (3,250,000) non-qualified stock options with a strike price equal to $0.166 per share were issued to directors per the terms of their agreements, or for reaching certain milestones: and lastly, six hundred ninety thousand (690,000) non-qualified stock options with strike prices ranging from $0.166 per share to $0.195 per share were issued to consultants per the terms of their agreements or as bonuses.

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Item 2. Management's Discussion And Analysis Or Plan Of Operation

Special Note Regarding Forward-looking Statements

Some of the statements under "Risk Factors," "Business" and elsewhere in this Quarterly Report on Form 10-QSB constitute forward-looking statements. These statements involve known and unknown risks, uncertainties and other factors that may cause our actual results, levels of activity, performance or achievements to be materially different from any future results, levels of activity, performance, or achievements expressed or implied by such forward-looking statements. Such factors include, among other things, those described under "Risk Factors" and elsewhere in this Quarterly Report on Form 10-QSB and in the "Risk Factors" section of our annual report on SEC Form 10-KSB filed with the Securities and Exchange Commission on April 17, 2007 and Form 10-KSB/A filed with the Securities and Exchange Commission on April 30, 2007 and May 8, 2007.

In some cases, you can identify forward-looking statements by terminology such as "may," "will," "should," "could," "expects," "plans," "intends," "anticipates," "believes," "estimates," "predicts," "potential" or "continue" or the negative of such terms or other comparable terminology.

Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance, or achievements. Moreover, neither we nor any other person assumes responsibility for the accuracy and completeness of such statements. We are under no duty to update any of the forward-looking statements after the date of this report.

The following information should be read in conjunction with the financial statements and the notes thereto. The analysis set forth below is provided pursuant to applicable Securities and Exchange Commission regulations and is not intended to serve as a basis for projections of future events.

Overview

IR BioSciences Holdings, Inc. is a development stage biotechnology company. Through our wholly-owned subsidiary ImmuneRegen BioSciences, Inc., we are engaged in the research and development of potential drug candidates, Homspera™ and its derivatives, Radilex™ and Viprovex®. We defined Radilex and Viprovex as derivatives of Homspera due to the potential difference in formulations and indications for use of such compounds. Our goal is to develop these potential drug candidates to be used as possible countermeasures for homeland security threats, including radiological, chemical and biological agents, such as influenza and anthrax. We hope there may exist not only a market for products related to biodefense through governmental purchasing, but there also may exist a potential commercial market for treatments of cancer treatment side-effects and seasonal influenza.

Our patents, patent applications and continued research are derived from discoveries made during research studies related to the function of Substance P, which is found in the body and has a large number of actions. These studies were funded by the Air Force Office of Scientific Research (AFOSR) in the early 1990s and were conducted by research scientists, including our co-founders Drs. Mark Witten and David Harris. In the course of research on Substance P, these scientists created a number of synthetic analogues, structural derivatives with slight chemical differences, for study. One of these, which we have named Homspera, is the basis for our drug development efforts and our intellectual property. All of our research and development efforts are early, pre-clinical stage and Homspera has only undergone exploratory studies to evaluate its biological activity in small animals. There can be no assurance that our interpretation of the results of our studies will prove to be accurate after further testing and our beliefs regarding the potential uses of our drug candidates may never materialize.

Our current focus is on the development of two potential formulations derived from Homspera, Radilex and Viprovex.

We are researching Radilex for use as a potential treatment for acute exposure to radiation. To date we have sponsored and co-sponsored radiation studies utilizing rodents. The results of these studies suggest Radilex may play a role in increased survival among tested rodents following exposure to lethal doses of gamma radiation. We believe that Radilex, if developed, may be an acceptable candidate to be marketed to governmental agencies for procurement. Further, we believe that a commercial market may exist for the use of Radilex as it relates to the treatment of radiation-induced side effects of cancer treatments, either as a stand alone treatment or as a co-therapeutic agent to be used with other therapies.

Viprovex is being researched by us for use in potential treatments of exposure to biological agents, such as infectious disease, which include influenza and anthrax. Based on early studies on Homspera and existing literature on Substance P, we are researching the efficacy of Viprovex as a potential treatment for exposure to chemical agents, such as formalin. To date we have sponsored studies related to the treatment of influenza, the exposure to anthrax spores and on exposure to formalin. We believe the results of these studies indicated potential efficacy in the use of Viprovex as both a stand alone treatment and an adjuvant, to be used in conjunction with other drugs. If Viprovex can be developed, we believe that potential applications may exist for sale to governments for the treatment of exposure to anthrax and pandemic influenza. In addition, we believe that potential commercial opportunities may exist for the treatment of seasonal influenza and other viral or bacterial infections, either as a stand-along drug or as an adjuvant to other existing drugs.

To date we have submitted preliminary study data to the U.S. Food and Drug Administration (FDA) and have been issued two Pre-Investigational New Drug (PIND) numbers, one for the potential use of Radilex in the treatment of acute radiation syndrome and the other for the potential use of Viprovex in the treatment of avian influenza.

We have filed patent applications and provisional patent applications, for the use of Homspera and derivatives thereof. We own four registered patents, two issued U.S. and two issued foreign patents, one of which represents nine countries in the European Union. We also have 34 pending patents, eleven pending U.S. patent applications and 23 pending foreign patent applications as well as six U.S. provisional patent applications.

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Our potential drug candidates, Radilex and Viprovex, are at early, pre-clinical stages of development and may not be shown to be safe or effective and may never receive regulatory approval. Neither Radilex nor Viprovex have yet been tested in large animals or humans. There is no guarantee that regulatory authorities will ever permit human testing of Radilex, Viprovex or any other potential products derived from Homspera. Even if such testing is permitted, none of Radilex, Viprovex or any other potential drug candidates, if any, derived from Homspera may be successfully developed or shown to be safe or effective.

The results of our pre-clinical studies and clinical trials may not be indicative of future clinical trial results. A commitment of substantial resources to conduct time-consuming research, pre-clinical studies and clinical trials will be required if we are to develop any commercial applications using Homspera or any derivatives thereof. Delays in planned patient enrollment in our future clinical trials may result in increased costs, program delays or both. None of our potential technologies may prove to be safe or effective in clinical trials. Approval of the FDA, or other regulatory approvals, including export license permissions, may not be obtained and even if successfully developed and approved, our potential applications may not achieve market acceptance. Any potential applications resulting from our programs may not be successfully developed or commercially available for a number of years, if at all.

To date, we have not obtained regulatory approval for or commercialized any applications using Homspera or any of its derivatives. We have incurred significant losses since our inception and we expect to incur annual losses for at least the next three years as we continue with our drug research and development efforts.

Results of Operations for the Three Month Periods Ended June 30, 2007 and June 30, 2006

Revenue

We have not generated any revenues from operations from our inception. We believe we will begin earning revenues from operations during calendar year 2009 as we transition from a development stage company.

Sales, General, and Administrative Expenses

Sales, general, and administrative expenses ("SG&A") were $1,141,908 for the three months ended June 30, 2007, an increase of $539,936 or approximately 90% compared to SG&A of $601,972 during the three months ended June 30, 2006. The increase is primarily due to higher costs for officer compensation, non-cash compensation and public relations. For the three months ended June 30, 2007, this amount consisted primarily of officer compensation of $155,625, public relations and marketing of $15,504, legal and accounting fees of $195,494, non-cash compensation costs of $274,380, research and development of $157,633, other consulting fees of $99,236 and payroll and related costs of $51,782.

We expect SG&A to increase during the coming twelve months as we continue to build out our infrastructure and to develop our potential drugs and therapeutics.

Interest Income (net)

Interest income (net) was $26,812 for the three months ended June 30, 2007, an increase of $41,869 or approximately 278% compared to interest expense (net) of $15,057 for the three months ended June 30, 2006. Interest income increased during the three months ended June 30, 2007 due to higher cash balances from the Private Placement in the fourth quarter of 2006.

We expect interest income to decrease during the coming twelve months as we use the proceeds from the Private Placement to fund operations.

Net Loss

For the reasons stated above and due to a one-time adjustment to Other Income in the three months ended June 30, 2006 that resulted in a net gain of $1,158,985 relating to the cost of penalty for late registration of shares (as described below)

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Results of Operations for the Six Month Periods Ended June 30, 2007 and June 30, 2006

Revenue

Sales, General, and Administrative Expenses

SG&A was $2,016,018 for the six months ended June 30, 2007, an increase of $852,902 or approximately 73% compared to SG&A of $1,163,116 during the six months ended June 30, 2006. The increase is primarily due to higher costs for officer compensation, non-cash compensation and public relations. For the six months ended June 30, 2007, this amount consisted primarily of officer compensation of $391,489, inclusive of an incentive bonus of $82,239 in cash for Michael K. Wilhelm, C.E.O. per the terms of his employment agreement, public relations and marketing of $130,766, legal and accounting fees of $309,765, non-cash compensation costs of $457,300, research and development of $234,467, other consulting fees of $125,090 and payroll and related costs of $71,608.

Interest Income (net)

Interest income (net) was $47,678 for the six months ended June 30, 2007, an increase of $62,569 or approximately 420% compared to interest expense of $14,891 for the six months ended June 30, 2006. Interest income increased during the six months ended June 30, 2007 due to higher cash balances from the Private Placement in the fourth quarter of 2006.

Net Loss

For the reasons stated above and due to a one-time adjustment to Other Income in the six months ended June 30, 2006 that resulted in a net gain of $557,457 relating to the cost of penalty for late registration of shares our net loss for the six months ended June 30, 2007 was $1,976,455 or $0.02 per share, an increase of $1,355,905 or approximately 219% compared to a net loss of $620,550 for the six months ended June 30, 2006.

Going Concern

Our independent certified public accountants have stated in their report included in our annual report on SEC Form 10-KSB filed with the Securities and Exchange Commission on April 17, 2007 and Form 10-KSB/A filed with the Securities and Exchange Commission on April 30, 2007 and on May 8, 2007, that we have incurred a net loss and negative cash flows from operations of $1,486,046 and $2,035,484 respectively, for the year ended December 31, 2006. This loss, in addition to a lack of operational history, raises substantial doubt about our ability to continue as a going concern. In the absence of significant revenue and profits, and since we do not expect to generate significant revenues in the foreseeable future, we, in order to fund operations, will be completely dependent on additional debt and equity financing arrangements. There is no assurance that any financing will be sufficient to fund our capital expenditures, working capital and other cash requirements for the fiscal year ending December 31, 2007. No assurance can be given that any such additional funding will be available or that, if available, can be obtained on terms favorable to us. If we are unable to raise needed funds on acceptable terms, we will not be able to develop or enhance our products, take advantage of future opportunities or respond to competitive pressures or unanticipated requirements. A material shortage of capital will require us to take drastic steps such as reducing our level of operations, disposing of selected assets or seeking an acquisition partner. If cash is insufficient, we will not be able to continue operations.

The Company expects losses to increase during the coming twelve months. The Company does not expect to begin to generate revenue in the coming twelve months, and our costs are likely to increase as continue our research and development efforts on our early, pre-clinical stage products and build out our corporate infrastructure.

Penalties for Late Registration

During the six months ended June 30, 2006, we accrued the issuance of 1,383,600 shares of common stock and warrants to purchase an additional 544,800 shares of common stock pursuant to a penalty calculation with regard to the late registration of shares sold in a private placement in October 2004.

In October 2004, we completed a private placement sale of shares of our common stock and warrants to purchase additional shares of common stock. We issued in the private placement an aggregate of 19,600,000 shares of our common stock and warrants to purchase 9,800,000 shares of our common stock. We agreed to register these shares along with the shares underlying these warrants within ninety days from the closing date of the transaction, or we would incur a penalty equivalent to an additional 2% of the shares and warrants to be registered for every 30 days that we fail to complete this registration. This penalty amounted to an aggregate of 461,200 shares and 181,600 warrants per 30 day period until such a time as this registration statement is made effective. As of June 30, 2006, we were required to issue an additional 6,625,907 shares of common stock and warrants to purchase an additional 2,724,000 shares of common stock. At the time these liabilities were incurred, the shares were valued at $2,448,511 and the warrants were valued at $744,177. The shares were valued at the market price of the Company's common stock at the time the liabilities were incurred. The warrants were valued utilizing the Black-Scholes valuation model. The aggregate amount of $555,973 was charged to operations as cost of penalty for late registration of shares during the three months ended June 30, 2006. The shares and warrants were re-valued at June 30, 2006, and the result of this re-valuation was to increase the value of the shares by $52,423 and to decrease the value of the warrants by $6,868. These decreases were credited to other (income) expense during the three months ended June 30, 2006. At June 30, 2006, the fair value of the common stock issuable under the penalty for late registration of shares is $2,186,549, and the fair value of the warrants issuable under the penalty for late registration of shares is $476,662. These amounts appear as current liabilities on the Company's condensed consolidated balance sheet at June 30, 2006.

The Company attempted to register the shares and warrants by filing a registration statement with the Securities and Exchange Commission on November 24, 2004, and amended this registration statement with pre-effective amendments no. 1, 2, 3 and 4 on July 20, 2005, November 16, 2005, February 22, 2006 and April 7, 2006, respectively. On July 10, 2006 the Company, pursuant to Rule 477 of Regulation C of the Securities Act of 1933, as amended, applied for an order granting the immediate withdrawal of its Registration Statement on Form SB-2.

In August 2006, we reached an agreement with the investors in the private placement of October 2004 which limits the number of warrants and shares which we are obligated to issue pursuant to the penalty calculation to an aggregate of 18% of the number of original number of shares and warrants issued in the October 2004 private placement. This agreement limits the number of shares and warrants issuable pursuant to the penalty calculation to an aggregate of 4,150,798 shares and warrants to purchase an additional 1,634,400 shares, respectively. This resulted in a decrease in the number of share issuable 2,475,107 (with a fair value of $816,785) and a decrease in the number of warrant shares of 974,587 (with a fair value of $177,789). This resulted in a net realized gain of $994,574 during the three months ended June 30, 2006.

In August 2006, we issued 4,150,798 shares and warrants to purchase 1,634,400 shares and relieved accrued liabilities in the aggregate amount of $1,053,904.

For the twelve months ended December 31, 2006 the Company marked to market the value of the shares and warrants issuable pursuant to the penalty calculation for an aggregate gain in the amount of approximately $445,673 and $123,505, respectively.

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Plan of Operations

We expect to continue to incur increasing operating losses for the foreseeable future, primarily due to our continued research and development activities attributable to Radilex, Viprovex or any other proposed product, if any, derived from Homspera and general and administrative activities.

Product Research and Development

We incurred an expense of $234,467 for the six months ended June 30, 2007 in research and development activities related to the development of Radilex and Viprovex versus an expense of $116,035 for the six months ended June 30, 2006. Due to our liquidity and limited cash available, our spending on research and development activities was limited. From our inception in October 2002, we have spent $1,261,064 in research and development activities. These costs only include the manufacture and delivery of our drug by third party manufacturers and payments to contract research organizations for consulting related to our studies and costs of performing such studies. Significant costs relating to research and development, such as compensation for Dr. Siegel have been classified in officer’s salaries for consistency of financial reporting.

We anticipate that during the next 12 months we will increase our research and development spending to a total of approximately $700,000 in an effort to further develop Radilex and Viprovex. This research and development cost estimate includes additional animal pharmacology studies, formulation and animal safety/toxicity studies. If we receive additional funds, through either investment funding or grants, we expect we will increase our research and development spending.

We believe we will be able to apply to the FDA for approval for the use of Radilex for the treatment of acute radiation syndrome and for approval for the use of Viprovex for the treatment of maladies caused by exposure to biological and chemical agents based upon the "animal efficacy rule." Therefore, we intend to apply for approval based upon a rule adopted by the FDA in 2002, titled "Approval of New Drugs When Human Efficacy Studies Are Not Ethical or Feasible" (Code of Federal Regulations, Title 21, Part 314, Subpart I), which is also referred to as the "animal efficacy rule." Pursuant to this rule, in situations where it would be unethical to conduct traditional Phase III efficacy studies in humans, as is the case with our applications relating to the treatment of maladies caused by exposure to high level gamma radiation and various chemical and biological agents, the FDA will review new drugs for approval on the basis of safety in humans and efficacy in relevant animal models. Through development under this rule, we believe that we could potentially incur less development costs as compared to the more traditional drug development model, as Phase III of the FDA required drug approval process is not required under the animal efficacy rule; however, there can be no assurances that we will be able to benefit from less development costs or that we will ever qualify for approval under the “animal efficacy rule”. Under either the animal efficacy rule or traditional efficacy rules, we will not have marketable applications unless and until our drug candidates complete all required safety studies and clinical trials and receive FDA approval in the United States or approval by regulatory agencies outside of the United States.

If we are successful in completing our studies and the results are as we anticipate, we intend to prepare and submit the necessary documentation to the FDA and other regulatory agencies for approval. If approval for Radilex and/or Viprovex is granted, we expect to begin efforts to commercialize our product, if any, immediately thereafter, however, since we are currently in the pre-clinical stage of development, it will take an indeterminate amount of time in development before we have a marketable drug, if ever.

We believe that initial revenues, if any, will likely be generated through partnerships, alliances and/or licensing agreements with pharmaceutical or biotechnology companies. Our focus during the next 24 months will be to identify those companies which we believe may have an interest in our proposed products and attempt to negotiate arrangements for potential partnerships, alliances and/or licensing arrangements. Alliances between pharmaceutical and biotechnology companies can take a variety of organizational forms and involve many different payment structures such as upfront payments, milestone payments, equity injections and royalty payments. To date, we have not entered into discussions with and have no agreements or arrangements with any such companies. Even if we are successful in entering into such a partnership or alliance or licensing our technology, we anticipate that the earliest we may begin to generate revenues from operations would be calendar 2009. There is no assurance that we will ever be successful in reaching such agreements or ever generate revenues from operations.

We will need to generate significant revenues from product sales and or related royalties and license agreements to achieve and maintain profitability. Through June 30, 2007, we had no revenues from any product sales, royalties or licensing fees, and have not achieved profitability on a quarterly or annual basis. Our ability to achieve profitability depends upon, among other things, our ability to develop products, obtain regulatory approval for products under development and enter into agreements for product development, manufacturing and commercialization. Moreover, we may never achieve significant revenues or profitable operations from the sale of any of our potential products or technologies.

Off-Balance Sheet Arrangements

There were no off-balance sheet arrangements as of June 30, 2007.

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Liquidity And Capital Resources

At June 30, 2007, we had current assets of $1,565,385 consisting of cash of $1,513,379 and other current assets of $52,006. At June 30, 2007, we also had current liabilities of $643,806, consisting of accounts payable and accrued liabilities of $593,806 and notes payable of $50,000. This resulted in net working capital at June 30, 2007 of $921,579. During the six months ended June 30, 2007, we used cash in operating activities of $1,231,110. From the date of inception (October 30, 2002) to June 30, 2007, we have had a net loss of $15,261,635 and has used cash of $7,225,052 in operating activities.

We currently have no revenue. There is no guarantee that our business model will be successful, or that we will be able to generate sufficient revenue to fund future operations. As a result, we expect our operations to continue to use net cash, and that we will be required to seek additional debt or equity financings during the coming quarters. Since inception, we have financed our operations through debt and equity financing. While we have raised capital to meet our working capital and financing needs in the past, additional financing is required in order to meet our current and projected cash flow deficits from operations and development of our product line. . We met our cash requirements from our inception through June 30,, 2007 via the private placement of $7,877,901 of our common stock and $908,628 from the issuance of notes payable, net of repayments.

Pursuant to our employment agreement with Michael Wilhelm, our President and Chief Executive Officer, dated December 16, 2002, we paid a salary of $125,000 and $175,000 to Mr. Wilhelm during the first and second years of his employment, respectively. Thereafter we paid through August 10, 2005, an annual salary of $250,000. On August 10, 2005, we entered into a new employment agreement with Mr. Wilhelm. The new employment agreement calls for a salary at the rate of $275,000 per annum and provides for bonus incentives. Mr. Wilhelm's salary is payable in regular installments in accordance with the customary payroll practices of our company. Further, pursuant to the terms of the change of control agreement between Mr. Wilhelm and us, we agree to pay Mr. Wilhelm his salary for a period of 18 months from the date an involuntary termination, payable in accordance with the Company's compensation practice. Involuntary termination is defined as the termination of Mr. Wilhelm employment by Company without cause or due to constructive termination at any time within one-year from a change of control event, as defined in the agreement.

Pursuant to our employment agreement with John Fermanis, our Chief Financial Officer, dated February 15, 2005, we paid a salary of $60,000 until the company completed a financing of $500,000 or more. This occurred on March 4, 2005 when the company completed a tender offer for warrants totaling $1,211,000 net of fees. From March 4, 2005, until December 31, 2005, we paid an annual salary of $85,000. Thereafter, we paid an annual salary of $98,000 for the second year ending December 31, 2006 and will pay an annual salary of $112,000 for the third year ending December 31, 2007. Mr. Fermanis' salary is payable in regular installments in accordance with the customary payroll practices of our company.

Pursuant to our employment agreement with Hal N. Siegel, our Senior Director of Product Development and Regulatory Affairs, dated October 23, 2006, we will pay an annual base salary of $200,000 for the first year and $210,000 for the second year. Mr. Siegel will also be eligible for discretionary bonuses under the Company's stock option plan during his employment. In addition, Mr. Siegel received options with a term of five years to purchase 200,000 shares of common stock of the Company. The options are exercisable at $0.20 per share. The employment agreement has a term of two years, subject to early termination provisions. Upon termination of Mr. Sigel's employment by the Company without cause or constructive termination, as defined in the agreement, the Company agrees to pay to Mr. Siegel the remainder of his salary for the year or six months salary, whichever is greater, and any accrued vacation. Further, pursuant to the terms of the change of control agreement between Mr. Siegel and us, we agree to pay Mr. Siegel his salary for a period of 18 months from the date an involuntary termination, payable in accordance with the Company's compensation practice. Involuntary termination is defined as the termination of Mr. Siegel's employment by Company without cause or due to constructive termination at any time within one-year from a change of control event, as defined in the agreement.

Since our inception, we have been seeking additional third-party funding. During such time, we have retained a number of different investment banking firms to assist us in locating available funding; however, we have not yet been successful in obtaining any of the long-term funding needed to make us into a commercially viable entity. During the period from October 2004 to June 2007, we were able to obtain financing of $9,097,736 from a series of private placements of our securities (which resulted in net proceeds to us of $7,877,901). Based on our current plan of operations all of our current funding is expected to be depleted by the end of January 2008. If we are not successful in generating sufficient liquidity from operations or in raising sufficient capital resources, it would have a material adverse effect on our business, results of operations, liquidity and financial condition.

While we have raised capital to meet our working capital and financing needs in the past through debt and equity financings, additional financing will be required in order to implement our business plan and to meet our current and projected cash flow deficits from operations and development. There can be no assurance that we will be able to consummate future debt or equity financings in a timely manner on a basis favorable to us, or at all. If we are unable to raise needed funds, we will not be able to develop or enhance our potential products, take advantage of future opportunities or respond to competitive pressures or unanticipated requirements. A material shortage of capital will require us to take drastic steps such as reducing our level of operations, disposing of selected assets or seeking an acquisition partner.

Until such time, if at all, as we receive adequate funding, we intend to continue to defer payment of all of our obligations which are capable of being deferred, which actions have resulted in some vendors demanding cash payment for their goods and services in advance, and other vendors refusing to continue to do business with us. We do not expect to generate a positive cash flow from our operations for at least several years, if at all, due to anticipated expenditures for research and development activities, administrative and marketing activities, and working capital requirements and expect to continue to attempt to raise further capital through one or more further private placements. Based on our operating expenses and anticipated research and development activities we believe we have sufficient working capital to meet or operating needs through January 2008. Thereafter, we believe that we will require an additional $2,500,000 to meet our expenses over the next 12 months.

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Acquisition or Disposition of Plant and Equipment

We did not dispose or acquire any significant property, plant or equipment during the six months ended June 30, 2007. We do not anticipate the sale of any significant property, plant or equipment during the next twelve months.

Number of Employees

From our inception through the period ended June 30, 2007, we have relied on the services of outside consultants for services and currently have seven total employees, five full-time employees and two part-time employees. Our full-time employees are Michael K. Wilhelm, our Chief Executive Officer; John N. Fermanis, our Chief Financial Officer; Hal N. Siegel, Ph.D., Senior Director, Product Development and Regulatory Affairs; a science associate, and, the fifth serves in an administrative role. In order for us to attract and retain quality personnel, we anticipate we will have to offer competitive salaries to future employees. We do not anticipate our employment base will significantly change during the next twelve months.

Trends, Risks and Uncertainties

We have sought to identify what we believe to be the most significant risks to our business, but we cannot predict whether, or to what extent, any of such risks may be realized nor can we guarantee that we have identified all possible risks that might arise. Investors should carefully consider all of such risk factors before making an investment decision with respect to our Common Stock.

Risk Factors

Other than with respect to the following risk factors, which have been updated and restated in their entirety below, there have been no material changes from the risk factors disclosed in the "Risk Factors" section of our the "Risk Factors" section of our annual report on SEC Form 10-KSB filed with the Securities and Exchange Commission on April 17, 2007 and Form 10-KSB/A filed with the Securities and Exchange Commission on April 30, 2007 and on May 8, 2007.

Risks Related to Our Financial Results

We have limited cash resources, an accumulated deficit, are not currently profitable and expect to incur significant expenses in the near future.

As of June 30, 2007, we had a working capital of $921,579. This amount consists of cash of $1,513,379 and other current assets of $52,006 less accounts payable and accrued liabilities of $593,806 and notes payable of $50,000. We have incurred a net loss of $15,261,635 for the period from our inception in October 2002 to June 30, 2007, and have always experienced negative cash flow. We expect to continue to experience negative cash flow and operating losses through at least 2010 and possibly thereafter. As a result, we will need to generate significant revenues to achieve profitability.

We may fail to become and remain profitable or we may be unable to fund our continuing losses, in which case our business may fail.

We are focused on product development and have not generated any revenue to date. We do not believe we will begin earning revenues from operations until the calendar year 2009 as we transition from a development stage company. We have incurred operating losses since our inception. Our net loss for the three months ended June 30, 2007 was $1,115,096. As of June 30, 2007, we had an accumulated deficit of $15,261,635.

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ITEM 3. Controls And Procedures

(a) Evaluation of disclosure controls and procedures.

Disclosure controls and procedures are controls and other procedures that are designed to ensure that information required to be disclosed by us in the reports that we file or submit under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), is recorded, processed, summarized and reported, within the time periods specified in the Securities and Exchange Commission's rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by us in the reports that we file under the Exchange Act is accumulated and communicated to our management, including our principal executive and financial officers, as appropriate to allow timely decisions regarding required disclosure.

As of the end of the period covered by this quarterly report, we conducted an evaluation, under the supervision and with the participation of our Chief Executive Officer and Chief Financial Officer, of our disclosure controls and procedures (as defined in Rules 13a-15(e) of the Exchange Act). Based on that evaluation, our Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures are effective in enabling the Company to record, process, summarize and report information required to be included in the Company's periodic SEC filings within the required time period.

(b) Changes in internal controls

There have been no changes in our internal control over financial reporting identified in connection with the evaluation required by paragraph (d) of Rule 13a-15 or 15d-15 under the Exchange Act that occurred during the quarter ended June 30, 2007 that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.

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PART II - Other Information

Item 1. Legal Proceedings

We are not currently a party to any material legal proceedings.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

On January 31, 2007, we issued 400,000 shares of common stock at a price of $0.155 per share to a consultant for services to be performed through June 2007. We charged the amount of $62,000 to prepaid services during the three months ended March 31, 2007. The securities were issued in reliance upon exemptions from registration pursuant to Section 4(2) under the Securities Act of 1933, as amended, and Rule 506 promulgated thereunder.

On January 31, 2007, we issued 100,000 shares of common stock at a price of $0.15 per share to a consultant for services to be performed through March 2007. We charged the amount of $15,000 to operations during the three months ended March 31, 2007. The securities were issued in reliance upon exemptions from registration pursuant to Section 4(2) under the Securities Act of 1933, as amended, and Rule 506 promulgated thereunder.

On January 3, 2007, we issued 5,482,600 restricted shares of our common stock to Joseph Stevens & Co., Inc. and its designees as commission for acting as placement agent for our private offering completed during the fourth quarter of 2006. Per the terms of our agreement, as additional commission, the placement agent, or its designees, were entitled to receive one share of common stock for each dollar of gross proceeds raised in the offering. These shares were shown as common stock subscribed on the Company’s balance sheet at December 31, 2006. The shares issued to the placement agent were offered in reliance upon exemptions from registration pursuant to Section 4(2) under the Securities Act of 1933, as amended, and Rule 506 promulgated thereunder.

In April 2007, the Company issued warrants to purchase 5,000,000 shares of common stock to a consultant. The warrants vest 750,000 immediately and 177,083 every month for the next two years. The Company charged to operations the amount of $89,800 the value of the warrants that vested during the three months ended June 30, 2007. The securities were issued in reliance upon exemptions from registration pursuant to Section 4(2) under the Securities Act of 1933, as amended, and Rule 506 promulgated thereunder.

Item 3. Defaults Upon Senior Securities

None.

Item 4: Submission Of Matters To A Vote Of Securities Holders

None.

Item 5: Other Information

Effective August 1, 2006, we converted a cash advance from a director into an unsecured senior promissory note in the amount of $50,000 bearing an annual interest rate of 12%. We repaid $56,000, the outstanding principal amount of the note plus accrued interest in the amount of $6,000, on August 6, 2007.

Item 6. Exhibits

(a)

Exhibits


31.1	Certification of Chief Executive Officer pursuant to Item 601(b)(31) of Regulation S-B, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

31.2	Certification of Chief Financial Officer pursuant to Item 601(b)(31) of Regulation S-B, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

32.1	Certifications of Chief Executive Officer pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.*

32.2	Certifications of Chief Financial Officer pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.*

This exhibit shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Securities Exchange Act of 1934, whether made before or after the date hereof and irrespective of any general incorporation language in any filings.

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Signatures

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized, on August 14, 2007.

	IR BioSciences Holdings, Inc.

	By:	/s/ Michael K. Wilhelm
		Michael K. Wilhelm
		President, Chief Executive Officer

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