x
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Annual
Report Pursuant to Section 13 or 15(d) of the Securities Exchange
Act of
1934
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For
the fiscal year ended December 31, 2006.
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OR
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o
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Transition
Report Pursuant to Section 13 or 15(d) of the Securities Exchange
Act of
1934
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DELAWARE
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13-3301899
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(State
or Other Jurisdiction of Incorporation or Organization)
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(I.R.S.
Employer Identification No.)
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4021
N. 75th Street, Suite 201, Scottsdale, AZ
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85251
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(Address
of Principal Executive Offices)
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(Zip
Code)
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Name
of Beneficial Owner (1)
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Common
Stock
Beneficially
Owned(2)
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Percentage
of
Common
Stock (3)
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||
Michael
K. Wilhelm
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9,030,659(4
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)
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7.4
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%
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John
N. Fermanis
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180,000(5
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)
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*
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%
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Hal
N. Siegel, Ph.D.
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249,900(6
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)
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*
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%
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Theodore
E. Staahl, M.D.
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3,489,464(7
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)
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3.0
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%
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Robert
J. Hariri, M.D., Ph.D.
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960,545(8
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)
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*
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%
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Mark
Witten
1501
N. Campbell Avenue
Room
3352
Tucson,
AZ 85724
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8,960,778(9
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)
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7.8
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%
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All
executive officers and directors as a group (5 persons)
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13,910,568(10
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11.4
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%
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Exhibit
Number
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Description
of Exhibit
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2.1
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Agreement
and Plan of Merger dated July 2, 2003 among the Registrant, GPN
Acquisition Corporation and ImmuneRegen BioSciences, Inc. (incorporated
by
reference to exhibit 2 of the Registrant's current report on Form
8-k
filed with the Securities and Exchange Commission on July 7,
2003).
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3.1
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Certificate
of Incorporation filed with the Delaware Secretary of State on June
4,
1985 (incorporated by reference to exhibit 3.1 of the Registrant's
annual
report on Form 10-KSB for the year ended December 31, 2001 filed
with the
Securities and Exchange Commission on April 16, 2002).
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3.1(a)
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Certificate
of Amendment filed with the Delaware Secretary of State on July 16,
1987
(incorporated by reference to exhibit 3.1(a) of the Registrant's
annual
report on Form 10-KSB for the year ended December 31, 2001 filed
with the
Securities and Exchange Commission on April 16, 2002).
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3.1(b)
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Certificate
of Amendment filed with the Delaware Secretary of State on February
3,
1992 (incorporated by reference to exhibit 3.1(b) of the Registrant's
annual report on Form 10-KSB for the year ended December 31, 2001
filed
with the Securities and Exchange Commission on April 16,
2002).
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3.1(c)
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Certificate
of Amendment filed with the Delaware Secretary of State on November
23,
1992 (incorporated by reference to exhibit 3.1(c) of the Registrant's
annual report on Form 10-KSB for the year ended December 31, 2001
filed
with the Securities and Exchange Commission on April 16,
2002).
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3.1(d)
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Certificate
of Amendment filed with the Delaware Secretary of State on December
15,
1994 (incorporated by reference to exhibit 3.1(d) of the Registrant's
annual report on Form 10-KSB for the year ended December 31, 2001
filed
with the Securities and Exchange Commission on April 16,
2002).
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3.1(e)
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Certificate
of Amendment filed with the Delaware Secretary of State on November
7,
1995 (incorporated by reference to exhibit 3.1(e) of the Registrant's
annual report on Form 10-KSB for the year ended December 31, 2001
filed
with the Securities and Exchange Commission on April 16,
2002).
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3.1(f)
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Certificate
of Amendment filed with the Delaware Secretary of State on December
30,
1996 (incorporated by reference to exhibit 3.1(f) of the Registrant's
annual report on Form 10-KSB for the year ended December 31, 2001
filed
with the Securities and Exchange Commission on April 16,
2002).
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3.1(g)
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Certificate
of Amendment filed with the Delaware Secretary of State on November
8,
2000 (incorporated by reference to exhibit 3.1(h) of the Registrant's
annual report on Form 10-KSB for the year ended December 31, 2001
filed
with the Securities and Exchange Commission on April 16,
2002).
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3.2
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Amended
and Restated Bylaws of the Registrant dated as of January 1, 2002
(incorporated by reference to exhibit 3(b) of the Registrant's annual
report on Form 10-KSB for the year ended December 31, 2001 filed
with the
Securities and Exchange Commission on April 16, 2002).
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4.1
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Specimen
Common Stock Certificate (incorporated by reference to exhibit 4.1
of the
Registrant's registration statement on Form SB-2 (File No. 333-120784)
filed with the Securities and Exchange Commission on November 24,
2004).
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Exhibit
Number
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Description
of Exhibit
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4.2
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2003
Stock Option, Deferred Stock and Restricted Stock Plan (incorporated
by
reference to exhibit 4.1 of the Registrant's registration statement
on
Form S-8 (file no. 333-113511) filed with the Securities and Exchange
Commission on March 11, 2004).
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4.3
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Form
of Warrant by and between the Registrant and each of the Investors
or
Creditors, as the case may be, who entered into an Agreement filed
as
Exhibit 10.6, 10.7, 10.8 or 10.9 herewith (incorporated by reference
to
exhibit 4.1 of the Registrant's current report on Form 8-K filed
with the
Securities and Exchange Commission on October 19,
2004).
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4.4
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Form
of Registration Rights (Annex A to Subscription Agreement) by and
between
the Registrant and each of the Investors who entered into the Agreements
filed as Exhibits 10.6 and 10.8 herewith (incorporated by reference
to
exhibit 4.2 of the Registrant's current report on Form 8-K filed
with the
Securities and Exchange Commission on October 19,
2004).
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4.5
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Form
of Anti-Dilution Rights (Annex B to Subscription Agreement) by and
between
the Registrant and each of the Investors who entered into the Agreements
filed as Exhibits 10.6 and 10.8 herewith (incorporated by reference
to
exhibit 4.3 of the Registrant's current report on Form 8-K filed
with the
Securities and Exchange Commission on October 19,
2004).
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4.6
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Promissory
Note issued from the Registrant to SBM Certificate Company as of
April 28,
2004 (incorporated by reference to exhibit 4.6 of the Registrant's
registration statement on Form SB-2 (File No. 333-120784) filed with
the
Securities and Exchange Commission on November 24,
2004).
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4.7
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Form
of Warrant by and between the Registrant and each of the investors
who
entered into the Subscription Agreements filed as Exhibits 10.18,
10.19
and 10.20 herewith (incorporated by reference from Exhibit 4.1 to
the
Quarterly Report on Form 10-QSB as filed with the Securities and
Exchange
Commission on November 14, 2006).
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10.1
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License
Agreement dated December 16, 2002 among ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant, David Harris and Mark Witten (incorporated
by reference to exhibit 10.4 of the Registrant's registration statement
on
Form SB-2 (File No. 333-120784) filed with the Securities and Exchange
Commission on November 24, 2004).
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10.1(a)
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First
Amendment to License Agreement dated December 20, 2002 among ImmuneRegen
BioSciences, Inc., a subsidiary of the Registrant, David Harris and
Mark
Witten (incorporated by reference to exhibit 10.4(a) of the Registrant's
registration statement on Form SB-2 (File No. 333-120784) filed with
the
Securities and Exchange Commission on November 24,
2004).
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10.1(b)
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Second
Amendment to License Agreement dated June 26, 2003 among ImmuneRegen
BioSciences, Inc., a subsidiary of the Registrant, David Harris and
Mark
Witten (incorporated by reference to exhibit 10.4(b) of the Registrant's
registration statement on Form SB-2 (File No. 333-120784) filed with
the
Securities and Exchange Commission on November 24,
2004).
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10.1(c)
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Assignment
Agreement dated February 23, 2005 between ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant and Mark Witten (incorporated by reference
to
exhibit 10.4(c) of the Registrant's registration statement on Form
SB-2
(File No. 333-120784) filed with the Securities and Exchange Commission
on
July 20, 2005).
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10.1(d)
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Assignment
Agreement dated February 23, 2005 among ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant, David Harris and Mark Witten (incorporated
by reference to exhibit 10.4(d) of the Registrant's registration
statement
on Form SB-2 (File No. 333-120784) filed with the Securities and
Exchange
Commission on July 20, 2005).
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10.1(e)
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Assignment
Agreement dated November 7, 2005 between ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant and Mark Witten (incorporated by reference
to
exhibit 10.4(e) of the Registrant's registration statement on Form
SB-2
(File No. 333-120784) filed with the Securities and Exchange Commission
on
November 16, 2005).
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10.1(f)
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Assignment
Agreement dated November 7, 2005 between ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant and Mark Witten (incorporated by reference
to
exhibit 10.4(f) of the Registrant's registration statement on Form
SB-2
(File No. 333-120784) filed with the Securities and Exchange Commission
on
February 22, 2006).
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10.1(g)
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Assignment
Agreement dated November 7, 2005 between ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant and Mark Witten (incorporated by reference
to
exhibit 10.4(g) of the Registrant's registration statement on Form
SB-2
(File No. 333-120784) filed with the Securities and Exchange Commission
on
November 16, 2005).
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10.1(h)
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Assignment
Agreement dated November 7, 2005 between ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant and Mark Witten (incorporated by reference
to
exhibit 10.4(h) of the Registrant's registration statement on Form
SB-2
(File No. 333-120784) filed with the Securities and Exchange Commission
on
November 16, 2005).
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10.2
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Lease
Agreement dated July 1, 2004 between ImmuneRegen BioSciences, Inc.,
a
subsidiary of the Registrant, and The Clayton Companies (incorporated
by
reference to exhibit 10.5 of the Registrant's registration statement
on
Form SB-2 (File No. 333-120784) filed with the Securities and Exchange
Commission on November 24, 2004).
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Exhibit
Number
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Description
of Exhibit
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10.3
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Form
of Subscription Agreement entered into as of October 13, 2004 between
the
Registrant and each of the Investors set forth on the Schedule of
Investors thereto (incorporated by reference to exhibit 10.1 of the
Registrant's current report on Form 8-K filed with the Securities
and
Exchange Commission on October 19, 2004).
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10.4
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Form
of Settlement Agreement entered into as of October 13, 2004 between
the
Registrant and each of the Creditors set forth on the Schedule of
Creditors thereto (incorporated by reference to exhibit 10.2 of the
Registrant's current report on Form 8-K filed with the Securities
and
Exchange Commission on October 19, 2004).
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10.5
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Form
of Subscription Agreement entered into as of October 26, 2004 between
the
Registrant and each of the Investors set forth on the Schedule of
Investors thereto (incorporated by reference to exhibit 10.1 of the
Registrant's current report on Form 8-K filed with the Securities
and
Exchange Commission on October 27, 2004).
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10.6
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Form
of Settlement Agreement entered into as of October 26, 2004 between
the
Registrant and each of the Creditors set forth on the Schedule of
Creditors thereto (incorporated by reference to exhibit 10.2 of the
Registrant's current report on Form 8-K filed with the Securities
and
Exchange Commission on October 27, 2004).
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10.7
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Employment
Agreement dated February 15, 2005 between the Registrant and John
N.
Fermanis (incorporated by reference to exhibit 10.10 of the Registrant's
Amendment No. 1 on Form 10-K/A to its annual report for the year
ended
December 31, 2004).
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10.8
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Employment
Agreement dated August 10, 2005 by and between the Registrant and
Michael
K. Wilhelm (incorporated by reference to exhibit 10.1 of the Registrant's
quarterly report on Form 10-QSB for the three months ended September
30,
2005).
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10.9
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Change
of Control Agreement dated August 10, 2005 by and between the Registrant
and Michael K. Wilhelm (incorporated by reference to exhibit 10.2
of the
Registrant's quarterly report on Form 10-QSB for the three months
ended
September 30, 2005).
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10.10
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Severance
Agreement dated November 7, 2005 by and between the Registrant and
Michael
K. Wilhelm (incorporated by reference to exhibit 10.3 of the Registrant's
quarterly report on Form 10-QSB for the three months ended September
30,
2005).
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10.11
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Authorization
for Regulatory Contact dated November 7, 2005 between ImmuneRegen
BioSciences, Inc., a subsidiary of the Registrant, and Synergos,
Inc.
(incorporated by reference to exhibit 10.14 of the Registrant's
registration statement on Form SB-2 (File No. 333-120784) filed with
the
Securities and Exchange Commission on February 22,
2006).
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10.12
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Proforma
invoice/quotation dated November 7, 2005 from Sigma-Aldrich, Inc.
to
ImmuneRegen BioSciences, Inc., a subsidiary of the Registrant
(incorporated by reference to exhibit 10.15 of the Registrant's
registration statement on Form SB-2 (File No. 333-120784) filed with
the
Securities and Exchange Commission on November 16,
2005).
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10.13
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Letter
of acceptance dated October 2, 2003, from Huntingdon Life Sciences
to
ImmuneRegen BioSciences, Inc., a subsidiary of the Registrant
(incorporated by reference to exhibit 10.16 of the Registrant's
registration statement on Form SB-2 (File No. 333-120784) filed with
the
Securities and Exchange Commission on February 22,
2006).
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10.14
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Price
Quotation dated June 27, 2003 received by ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant from AppTec Laboratory Services (incorporated
by reference to exhibit 10.17 of the Registrant's registration statement
on Form SB-2 (File No. 333-120784) filed with the Securities and
Exchange
Commission on February 22, 2006).
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Exhibit
Number
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Description
of Exhibit
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10.15
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Consulting
Agreement dated March 15, 2005 between ImmuneRegen BioSciences, Inc.,
a
subsidiary of the Registrant and Dr. Hal Siegel, Ph.D. (Siegel
Consultancy) (incorporated by reference to exhibit 10.18 of the
Registrant's registration statement on Form SB-2 (File No. 333-120784)
filed with the Securities and Exchange Commission on February 22,
2006).
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10.16
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Consulting
Agreement dated November 3, 2005 between ImmuneRegen BioSciences,
Inc., a
subsidiary of the Registrant and Dr. Jack Caravelli, Ph.D (incorporated
by
reference to exhibit 10.19 of the Registrant's registration statement
on
Form SB-2 (File No. 333-120784) filed with the Securities and Exchange
Commission on February 22, 2006).
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10.17
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Consulting
Agreement dated July 29, 2005 between ImmuneRegen BioSciences, Inc.,
a
subsidiary of the Registrant and Dr. Kelly McQueen, MD, MPH (incorporated
by reference to exhibit 10.20 of the Registrant's registration statement
on Form SB-2 (File No. 333-120784) filed with the Securities and
Exchange
Commission on February 22, 2006).
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10.18
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Form
of Subscription Agreement entered into as of December 6, 2006 between
the
Registrant and each of the Investors set forth on the Schedule of
Investors contained therein (incorporated by reference from Exhibit
10.1
to the Report on Form 8-K as filed with the Securities and Exchange
Commission on December 7, 2006).
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10.19
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Form
of Subscription Agreement entered into as of October 4, 2006 between
the
Registrant and each of the Investors set forth on the Schedule of
Investors contained therein. (incorporated by reference from Exhibit
10.2
to the Quarterly Report on Form 10-QSB as filed with the Securities
and
Exchange Commission on November 14, 2006).
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10.20
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Form
of Subscription Agreement entered into as of October 26, 2006 between
the
Registrant and each of the Investors set forth on the Schedule of
Investors contained therein (incorporated by reference from Exhibit
10.2
to the Quarterly Report on Form 10-QSB as filed with the Securities
and
Exchange Commission on November 14, 2006).
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10.21
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Standard
Form of Director Indemnification Agreement.
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14.1
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Code
of Ethics, dated April 29, 2005.
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21.1
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Subsidiaries
of Registrant (incorporated by reference to exhibit 21.1 of the
Registrant's registration statement on Form SB-2 (File No. 333-120784)
filed with the Securities and Exchange Commission on November 24,
2004).
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23.1
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Consent
of Russell Bedford Stefanou Mirchandani LLP
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31.1
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Certification
of Chief Executive Officer pursuant to Item 601(b)(31) of Regulation
S-B,
as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of
2002.
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31.2
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Certification
of Chief Financial Officer pursuant to Item 601(b)(31) of Regulation
S-B,
as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of
2002.
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32.1
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Certifications
of Chief Executive Officer pursuant to 18 U.S.C. Section 1350 as
adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of
2002.*
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32.2
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Certifications
of Chief Financial Officer pursuant to 18 U.S.C. Section 1350 as
adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of
2002.*
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*
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This
exhibit shall not be deemed "filed" for purposes of Section 18 of
the
Securities Exchange Act of 1934 or otherwise subject to the liabilities
of
that section, nor shall it be deemed incorporated by reference in
any
filing under the Securities Act of 1933 or the Securities Exchange
Act of
1934, whether made before or after the date hereof and irrespective
of any
general incorporation language in any
filings.
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IR
BIOSCIENCES HOLDINGS, INC.
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Date:
May 8, 2007
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By:
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/s/
Michael K.
Wilhelm
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Michael
K. Wilhelm
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President
and Chief Executive Officer
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SIGNATURE
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TITLE
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DATE
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/s/
Michael K.
Wilhelm
Michael
K. Wilhelm
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Chief
Executive Officer, President and Director (Principal Executive
Officer)
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May
8, 2007
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/s/
John N.
Fermanis
John
N. Fermanis
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|
Chief
Financial Officer (Principal Financial and Accounting
Officer)
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May
8, 2007
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/s/
Hal N.
Siegel
Hal
N. Siegel, Ph.D.
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Director
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May
8, 2007
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/s/
Theodore E.
Staahl
Theodore
E. Staahl, M.D.
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Director
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May
8, 2007
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/s/
Robert J.
Hariri
Robert
J. Hariri, M.D., Ph.D.
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Director
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|
May
8, 2007
|