FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * BIENAIME JEAN JACQUES   2. Issuer Name and Ticker or Trading Symbol BIOMARIN PHARMACEUTICAL INC [BMRN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chief Executive Officer (Last) (First) (Middle) C/O BIOMARIN PHARMACEUTICAL INC., 770 LINDARO ST. 3. Date of Earliest Transaction (Month/Day/Year) 12/24/2014 (Street) SAN RAFAEL, CA 94901 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 12/24/2014(1) 12/24/2014 M   3,000 A $ 12.99 46,195 I Shares held by Bienaime Family Trust (2) Common Stock 12/24/2014(1) 12/24/2014 S   3,000 D $ 88.731 (3) 43,195 I Shares held by Bienaime Family Trust (2) Common Stock 12/24/2014(1) 12/24/2014 S   2,000 D $ 88.731 (3) 227,157 D

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Stock Option (right to buy Common Stock)

$ 12.99

12/24/2014(1)

12/24/2014

M

3,000

11/11/2006(4)

05/10/2016

Common Stock

3,000

$ 0

64,500 (5)

I

Shares Held by Bienaime Family Trust (2)

Stock Option (right to buy Common Stock)

$ 12.99

11/11/2006(4)

05/10/2016

Common Stock

10,000

10,000

I

Held in irrevocable trust for Guillaume Bienaime (6)

Stock Option (right to buy Common Stock)

$ 12.99

11/11/2006(4)

05/10/2016

Common Stock

10,000

10,000

I

Held in irrevocable trust for Pierre Bienaime (6)

Stock Option (right to buy Common Stock)

$ 12.99

11/11/2006(4)

05/10/2016

Common Stock

10,000

10,000

I

Held in irrevocable trust for Paul Bienaime (6)

Stock Option (right to buy Common Stock)

$ 12.99

11/11/2006(4)

05/10/2016

Common Stock

10,000

10,000

I

Held in irrevocable trust for Marc Bienaime (6)

Stock Option (right to buy Common Stock)

$ 12.99

11/11/2006(4)

05/10/2016

Common Stock

20,000

20,000

I

Held in irrevocable trust for Aurelie Mitsuki Bienaime & Anais Kimiko Bienaime (6)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
BIENAIME JEAN JACQUES C/O BIOMARIN PHARMACEUTICAL INC. 770 LINDARO ST. SAN RAFAEL, CA 94901	X		Chief Executive Officer

Signatures

/s/ Laura Randall Woodhead, Attorney-in-Fact		12/29/2014
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Trade made pursuant to a 10b5-1 plan executed November 6, 2014
(2)	The reporting person an his spouse act as trustees for the Bienaime Family Trust
(3)	The price in column 4 is an average weighted price. The price actually received ranged from $87.00 to $89.41. The issuing person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the amount of shares sold at each price within the range.
(4)	Original option grant vests 6/48ths on November 11, 2006, and 1/48th on the 11th of every month thereafter.
(5)	Reflects the number of stock options outstanding after the transaction from this specific stock option grant.
(6)	The reporting person's spouse is the trustee of each child's trust.

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