PAGE  1
000 A000000 01/31/2009
000 C000000 0001059386
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 VAN KAMPEN SENIOR INCOME TRUST
001 B000000 811-08743
001 C000000 2127625260
002 A000000 522 FIFTH AVENUE
002 B000000 NEW YORK
002 C000000 NY
002 D010000 10036
003  000000 N
004  000000 N
005  000000 N
006  000000 N
007 A000000 N
007 B000000  0
007 C010100  1
007 C010200  2
007 C010300  3
007 C010400  4
007 C010500  5
007 C010600  6
007 C010700  7
007 C010800  8
007 C010900  9
007 C011000 10
007 C011100 11
007 C011200 12
007 C011300 13
007 C011400 14
007 C011500 15
007 C011600 16
007 C011700 17
007 C011800 18
007 C011900 19
007 C012000 20
007 C012100 21
007 C012200 22
007 C012300 23
007 C012400 24
007 C012500 25
007 C012600 26
007 C012700 27
007 C012800 28
007 C012900 29
      PAGE  2
007 C013000 30
007 C013100 31
007 C013200 32
007 C013300 33
007 C013400 34
007 C013500 35
007 C013600 36
007 C013700 37
007 C013800 38
007 C013900 39
007 C014000 40
008 A000001 VAN KAMPEN ASSET MANAGEMENT
008 B000001 A
008 C000001 801-1669
008 D010001 NEW YORK
008 D020001 NY
008 D030001 10036
010 A000001 VAN KAMPEN INVESTMENTS INC.
010 B000001 8-19412
010 C010001 NEW YORK
010 C020001 NY
010 C030001 10036
012 A000001 COMPUTERSHARE TRUST COMPANY, N.A.
012 B000001 85-11340
012 C010001 PROVIDENCE
012 C020001 RI
012 C030001 02940
012 C040001 3078
013 A000001 DELOITTE & TOUCHE LLP
013 B010001 CHICAGO
013 B020001 IL
013 B030001 60606
014 A000001 ARIGIL MENKUL DEGERLER A.S.
014 B000001 8-00000
014 A000002 CHINA INTL CAPITAL CORP. HONG KONG SEC.LTD
014 B000002 8-00000
014 A000003 H.C. SECURITIES AND INVESTMENTS
014 B000003 8-00000
014 A000004 BANK MORGAN STANLEY AG
014 B000004 8-00000
014 A000005 MORGAN STANLEY DEAN WITTER C.T.V.M. S.A.
014 B000005 8-00000
014 A000006 MORGAN STANLEY FUTURES (HONG KONG) LTD
014 B000006 8-00000
014 A000007 MORGAN STANLEY HONG KONG SECURITIES LTD
014 B000007 8-00000
014 A000008 MORGAN STANLEY & CO. INC.
014 B000008 8-15869
014 A000009 MORGAN STANLEY & CO. INTERNATIONAL PLC
014 B000009 8-00000
014 A000010 MORGAN STANLEY ASIA (SINGAPORE) SEC PTE
      PAGE  3
014 B000010 8-00000
014 A000011 MORGAN STANLEY CANADA LTD
014 B000011 8-00000
014 A000012 MORGAN STANLEY SECURITIES LTD
014 B000012 8-00000
014 A000013 MORGAN STANLEY DEAN WITTER AUSTRALIA SEC.LTD
014 B000013 8-00000
014 A000014 MORGAN STANLEY DEAN WITTER AUSTRALIA LTD
014 B000014 8-00000
014 A000015 MORGAN STANLEY, S.V. S.A.
014 B000015 8-00000
014 A000016 MORGAN STANLEY DEAN WITTER ASIA(SINGAPORE)PTE
014 B000016 8-00000
014 A000017 MORGAN STANLEY JAPAN SECURITIES CO. LTD
014 B000017 8-00000
014 A000018 MORGAN STANLEY INDIA CO. PRIVATE LTD
014 B000018 8-00000
014 A000019 OOO MORGAN STANLEY BANK
014 B000019 8-00000
014 A000020 MORGAN STANLEY DISTRIBUTION INC.
014 B000020 8-44766
014 A000021 MORGAN STANLEY DISTRIBUTORS INC.
014 B000021 8-45262
014 A000022 MORGAN STANLEY MARKET PRODUCTS INC.
014 B000022 8-37795
014 A000023 MS SECURITIES SERVICES INC.
014 B000023 8-26804
014 A000024 PRIME DEALER SERVICES CORP.
014 B000024 8-47025
014 A000025 VAN KAMPEN FUNDS INC.
014 B000025 8-19412
014 A000026 MORGAN STANLEY ASIA LTD
014 B000026 8-00000
014 A000027 MORGAN STANLEY TAIWAN LTD
014 B000027 8-00000
014 A000028 BLOCK INTEREST DISCOVERY SERVICE
014 B000028 8-00000
014 A000029 BETTER ALTERNATIVE TRADING SYSTEM
014 B000029 8-00000
014 A000030 MUNICENTER
014 B000030 8-00000
014 A000031 RMB MORGAN STANLEY
014 B000031 8-00000
014 A000032 HTI VALORI MOBILIARE S.A.
014 B000032 8-00000
015 A000001 STATE STREET BANK AND TRUST COMPANY
015 B000001 C
015 C010001 BOSTON
015 C020001 MA
015 C030001 02111
015 E010001 X
      PAGE  4
018  000000 Y
019 A000000 Y
019 B000000   84
019 C000000 VANKAMPENF
020 C000001      0
020 C000002      0
020 C000003      0
020 C000004      0
020 C000005      0
020 C000006      0
020 C000007      0
020 C000008      0
020 C000009      0
020 C000010      0
021  000000        0
022 A000001 JPMORGAN CHASE BANK
022 B000001 13-3224016
022 C000001      5939
022 D000001    110869
022 A000002 DEUTSCHE BANK AG
022 B000002 13-2730828
022 C000002      4241
022 D000002     66958
022 A000003 CITBANK
022 B000003 13-3187336
022 C000003       749
022 D000003     67505
022 A000004 CREDIT SUISSE FIRST BOSTON
022 B000004 13-5659485
022 C000004      4758
022 D000004     42116
022 A000005 BANK OF AMERICA N.A.
022 B000005 56-2058405
022 C000005      8601
022 D000005     36928
022 A000006 WACHOVIA BANK N.A.
022 B000006 56-0276690
022 C000006      1528
022 D000006     24981
022 A000007 GOLDMAN SACHS
022 B000007 13-5108880
022 C000007      9118
022 D000007     14649
022 A000008 BARCLAYS BANK PLC
022 C000008      3436
022 D000008     12628
022 A000009 ROYAL BANK OF SCOTLAND PLC
022 C000009         0
022 D000009     16005
022 A000010 UBS AG
022 B000010 13-2932996
      PAGE  5
022 C000010         0
022 D000010     15506
023 C000000      46342
023 D000000     457024
024  000000 N
025 D000001       0
025 D000002       0
025 D000003       0
025 D000004       0
025 D000005       0
025 D000006       0
025 D000007       0
025 D000008       0
026 A000000 N
026 B000000 Y
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 Y
026 G010000 N
026 G020000 N
026 H000000 N
027  000000 N
028 A010000         0
028 A020000         0
028 A030000         0
028 A040000         0
028 B010000         0
028 B020000         0
028 B030000         0
028 B040000         0
028 C010000         0
028 C020000         0
028 C030000         0
028 C040000         0
028 D010000         0
028 D020000         0
028 D030000         0
028 D040000         0
028 E010000         0
028 E020000         0
028 E030000         0
028 E040000         0
028 F010000         0
028 F020000         0
028 F030000         0
028 F040000         0
028 G010000         0
028 G020000         0
028 G030000         0
028 G040000         0
      PAGE  6
028 H000000         0
030 A000000      0
030 B000000  0.00
030 C000000  0.00
031 A000000      0
031 B000000      0
032  000000      0
033  000000      0
035  000000      0
036 B000000      0
038  000000      0
042 A000000   0
042 B000000   0
042 C000000   0
042 D000000   0
042 E000000   0
042 F000000   0
042 G000000   0
042 H000000   0
043  000000      0
044  000000      0
045  000000 Y
046  000000 N
047  000000 Y
048  000000  0.850
048 A010000        0
048 A020000 0.000
048 B010000        0
048 B020000 0.000
048 C010000        0
048 C020000 0.000
048 D010000        0
048 D020000 0.000
048 E010000        0
048 E020000 0.000
048 F010000        0
048 F020000 0.000
048 G010000        0
048 G020000 0.000
048 H010000        0
048 H020000 0.000
048 I010000        0
048 I020000 0.000
048 J010000        0
048 J020000 0.000
048 K010000        0
048 K020000 0.000
049  000000 N
050  000000 N
051  000000 N
052  000000 N
      PAGE  7
053 A000000 N
054 A000000 Y
054 B000000 N
054 C000000 N
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 Y
054 H000000 N
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 N
054 M000000 Y
054 N000000 N
054 O000000 Y
055 A000000 N
055 B000000 N
056  000000 N
057  000000 N
058 A000000 N
059  000000 Y
060 A000000 Y
060 B000000 Y
061  000000        0
062 A000000 Y
062 B000000   0.0
062 C000000   0.0
062 D000000   0.0
062 E000000   0.0
062 F000000   0.0
062 G000000   0.0
062 H000000   0.0
062 I000000   0.0
062 J000000   1.6
062 K000000   0.0
062 L000000   0.0
062 M000000   0.0
062 N000000   0.0
062 O000000   0.0
062 P000000   0.0
062 Q000000 184.5
062 R000000   0.0
063 A000000   0
063 B000000  4.4
064 A000000 Y
064 B000000 Y
065  000000 Y
066 A000000 N
067  000000 N
068 A000000 N
      PAGE  8
068 B000000 N
069  000000 N
070 A010000 Y
070 A020000 N
070 B010000 N
070 B020000 N
070 C010000 Y
070 C020000 N
070 D010000 N
070 D020000 N
070 E010000 Y
070 E020000 N
070 F010000 N
070 F020000 N
070 G010000 Y
070 G020000 N
070 H010000 N
070 H020000 N
070 I010000 N
070 I020000 N
070 J010000 Y
070 J020000 Y
070 K010000 Y
070 K020000 N
070 L010000 Y
070 L020000 Y
070 M010000 Y
070 M020000 N
070 N010000 Y
070 N020000 N
070 O010000 Y
070 O020000 Y
070 P010000 Y
070 P020000 N
070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000     76598
071 B000000    573003
071 C000000   1474313
071 D000000    5
072 A000000  6
072 B000000    60803
072 C000000        1
072 D000000        0
072 E000000     1753
072 F000000     6354
072 G000000     1495
072 H000000        0
072 I000000       15
      PAGE  9
072 J000000      255
072 K000000        0
072 L000000       87
072 M000000       13
072 N000000       66
072 O000000        0
072 P000000     4817
072 Q000000      102
072 R000000       53
072 S000000      168
072 T000000        0
072 U000000        0
072 V000000        0
072 W000000     3639
072 X000000    17064
072 Y000000        0
072 Z000000    45493
072AA000000        0
072BB000000   211373
072CC010000        0
072CC020000   439903
072DD010000    42752
072DD020000        0
072EE000000        0
073 A010000   0.2400
073 A020000   0.0000
073 B000000   0.0000
073 C000000   0.0000
074 A000000        0
074 B000000        0
074 C000000     8215
074 D000000        0
074 E000000        0
074 F000000      161
074 G000000        0
074 H000000        0
074 I000000   941813
074 J000000     9794
074 K000000        0
074 L000000     7074
074 M000000       63
074 N000000   967120
074 O000000     1250
074 P000000      955
074 Q000000    81000
074 R010000        0
074 R020000        0
074 R030000        0
074 R040000    23345
074 S000000   350070
074 T000000   510500
      PAGE  10
074 U010000   180010
074 U020000        0
074 V010000     2.84
074 V020000     0.00
074 W000000   0.0000
074 X000000      580
074 Y000000        0
075 A000000        0
075 B000000  1482933
076  000000     2.80
077 A000000 Y
077 B000000 N
077 C000000 N
077 D000000 N
077 E000000 Y
077 F000000 N
077 G000000 N
077 H000000 N
077 I000000 N
077 J000000 N
077 K000000 N
077 L000000 N
077 M000000 N
077 N000000 N
077 O000000 N
077 P000000 N
077 Q010000 N
077 Q020000 N
077 Q030000 N
078  000000 N
080 C000000        0
081 B000000   0
082 B000000        0
083 B000000        0
084 B000000        0
086 A010000      0
086 A020000      0
086 B010000      0
086 B020000      0
086 C010000      0
086 C020000      0
086 D010000  14000
086 D020000 350000
086 E010000      0
086 E020000      0
086 F010000      0
086 F020000      0
087 A010000 COMMON
087 A020000 920961109
087 A030000 VVR
088 A000000 N
      PAGE  11
088 B000000 N
088 C000000 N
088 D000000 Y
SIGNATURE   AMY JARAMSEK
TITLE       ASSISTANT TREASURER