SCHEDULE 14A INFORMATION

 

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Rigel Pharmaceuticals, Inc.

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*** Exercise Your Right to Vote *** IMPORTANT NOTICE Regarding the Availability of Proxy Materials RIGEL PHARMACEUTICALS, INC. Meeting Information Meeting Type: Annual Meeting of Stockholders For holders as of: 4/1/09 Date: 5/28/2009 Time: 10:00 a.m. PT RIGEL RIGEL PHARMACEUTICALS, INC. C/O INVESTOR RELATIONS 1180 VETERANS BLVD. SOUTH SAN FRANCISCO, CA 94080 Location: Rigel Pharmaceuticals, Inc. 1180 Veterans Boulevard South San Francisco, CA 94080 Directions to Meeting: For directions to the meeting please visit www.rigel.com/rigel/contact You are receiving this communication because you hold shares in Rigel Pharmaceuticals, Inc. This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at www.proxyvote.com or easily request a paper or electronic copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting. See the reverse side of this notice to obtain proxy materials and voting instructions. M13226-P74486_P74349

 

— Before You Vote — How to Access the Proxy Materials Proxy Materials Available to VIEW or RECEIVE: NOTICE AND PROXY STATEMENT FORM 10-K LETTER TO STOCKHOLDERS How to View Online: Have the 12-Digit Control Number available (located on the following page) and visit: www.proxyvote.com. How to Request and Receive a PAPER or E-MAIL Copy: If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request: 1) BY INTERNET: www.proxyvote.com 2) BY TELEPHONE: 1-800-579-1639 3) BY E-MAIL*: sendmaterial@proxyvote.com * If requesting materials by e-mail, please send a blank e-mail with the 12-Digit Control Number (located on the following page) in the subject line. Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. To facilitate timely delivery, please make the request as instructed above on or before 5/22/09. — How To Vote — Please Choose One of the Following Voting Methods Vote In Person: Many stockholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares. Vote By Internet: To vote now by Internet, go to www.proxyvote.com. Have the 12-Digit Control Number available and follow the instructions. Vote By Mail: You can vote by mail by requesting a paper or electronic copy of the proxy materials, which will include a proxy card. M13227-P74486_P74349

 

Voting Items The Board of Directors recommends a vote “FOR” each of the following two proposals: 1. To elect the following three nominees for director to the Board of Directors of the Company, to hold office until the 2012 Annual Meeting of Stockholders: 01) James M. Gower 02) Gary A. Lyons 03) Donald G. Payan, M.D. 2. To ratify the selection by the Audit Commitee of the Board of Directors of Ernst & Young LLP as the independent registered public accounting firm of the Company for its fiscal year ending December 31, 2009. The Board knows of no other matters that will be presented for consideration at the Annual Meeting. If any other matters are properly brought before the meeting, it is the intention of the persons named in the proxy card to vote on those matters in accordance with their best judgement. M13228-P74486_P74349

 

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