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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549



FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934



Date of Report (Date of earliest event reported): March 31, 2003

Vertex Pharmaceuticals Incorporated
(Exact name of registrant as specified in its charter)

MASSACHUSETTS
(State or other jurisdiction
of Incorporation)
  000-19319
(Commission
File Number)
  04-3039129
(IRS Employer
Identification No.)

130 WAVERLY STREET
CAMBRIDGE, MA 02139
(Address of principal executive offices) (Zip Code)

Registrant's telephone number, including area code: (617) 444-6100




ITEM 5. OTHER EVENTS.

On January 2, 2003, Vicki L. Sato, the Company's President, entered into a plan with Goldman, Sachs & Co., pursuant to which Goldman will undertake to sell, subject to a limit order, an aggregate of 200,000 shares of the Company's stock issuable upon exercise of options held by Dr. Sato. Sales under the plan are to begin no earlier than 90 days after adoption of the plan, and will take place at specified intervals between April 2, 2003 and March 31, 2004.




SIGNATURES

        Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

    VERTEX PHARMACEUTICALS INCORPORATED
(Registrant)

Date: March 31, 2003

 

By:

/s/  
IAN F. SMITH      
Ian F. Smith
Vice President and Chief Financial Officer



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SIGNATURES