Filed Pursuant to Rule 424(b)(3)
                                                Registration No. 333-109070


                               CEL-SCI CORPORATION

                              Prospectus Supplement
                     (To Prospectus dated February 11, 2005)

      Prospective investors should read this prospectus supplement and the
related prospectus carefully before investing in CEL-SCI's common stock. Both
documents contain information prospective investors should consider when making
an investment decision.

      The attached prospectus relates to the resale of shares acquired by
Rubicon Group Ltd. pursuant to an equity line of credit. Because Rubicon Group
Ltd. may sell some or all of these shares, and since there are currently no
agreements, arrangements or understandings with respect to the sale of any of
these shares, CEL-SCI cannot estimate the actual number of shares that Rubicon
Ltd. will hold after the completion of the offering.

      The following provides information concerning the latest drawdown
requested by CEL-SCI under the equity line of credit.

      Date of          Shares         Average Sale       Net Proceeds
       Sale             Sold         Price Per Share     to CEL-SCI
      -------          ------        ---------------     -----------

    12-22-05           626,600            $0.48           $300,000


      CEL-SCI's common stock is quoted on the American Stock Exchange under the
symbol "CVM". On December 21, 2005 the closing price for one share of CEL-SCI's
common stock was $0.50.

      CEL-SCI expects to use the proceeds from the sale of these shares for
general and administrative expenses, research and clinical trials.










          The date of this prospectus supplement is December 22, 2005.