• 48% shorter mean length of stay among those treated compared with those not treated (P<0.001)
• 51% fewer readmissions compared with the pre-intervention period (P<0.001)
• 33% fewer instances of return to the Emergency Department compared with the pre-intervention period (P=0.005)
• Only 12.8% of patients who received treatment required antibiotics at 72hrs – 30 days post-surgery compared with 23.1% of patients who had not received treatment (P<0.001)

One of Canada’s top research hospitals, The Ottawa Hospital, has presented results from its 2022 quality improvement study into patient outcomes after spinal surgery when using nasal photodisinfection for the prevention of surgical site infections (‘SSIs’). The study results were presented for the first time at the 2023 Annual Scientific Conference of the Canadian Spine Society in Quebec on Thursday 2 March, 2023.

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Ondine Biomedical’s Nasal Photodisinfection Reduces Hospital Length of Stay, Readmissions and Antibiotic Use in Substantial Study at Major Ottawa Hospital (Photo: Business Wire)

The podium presentation showed that spine surgery patients treated with Ondine Biomedical’s Steriwave™ nasal photodisinfection had a 48% shorter mean length of stay in hospital compared with those not treated (LOS: 5.58 days vs. 10.67, P<0.001), and significantly fewer treated patients required antibiotics at 72hrs – 30 days post-surgery compared those not treated (12.8% vs. 23.1%, P<0.001). Additionally, there was 51% reduction in the rate of readmissions (3.4% vs. 7%, P<0.001) and 33% reduction in the rate of return to the emergency department (6.9% vs. 10.3%, P=0.005) in the intervention period compared to the pre-intervention period.

The Ottawa Hospital is a leading Canadian academic health sciences centre caring for 1.2 million patients across Eastern Ontario. It was awarded an innovation award from the Ontario Surgical Quality Improvement Network in January 2023 for the Steriwave study, which commenced in January 2022. Steriwave nasal photodisinfection was developed by Canadian life sciences company, Ondine Biomedical.

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**ENDS**

About Ondine Biomedical Inc.

Ondine Biomedical Inc. is a Canadian company innovating in the field of photodisinfection therapies. Ondine has a pipeline of investigational products, based on its proprietary photodisinfection platform, in various stages of development. Products beyond nasal photodisinfection include therapies for a variety of medical indications such as chronic sinusitis, ventilator-associated pneumonia, burns, and other indications.

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