UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

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                                    FORM 6-K

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                            REPORT OF FOREIGN ISSUER

                       Pursuant to Rule 13a-16 or 15d-16
                     of the Securities Exchange Act of 1934


                                OCTOBER 25, 2007


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                                NOVO NORDISK A/S
             (Exact name of Registrant as specified in its charter)


                                    NOVO ALLE
                               DK-2880, BAGSVAERD
                                     DENMARK
                    (Address of principal executive offices)

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Indicate by check mark whether the registrant files or will file annual reports
under cover of Form 20-F or Form 40-F

                       Form 20-F [X]     Form 40-F [ ]


Indicate by check mark whether the registrant by furnishing the information
contained in this Form is also thereby furnishing the information to the
Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.

                             Yes [ ]     No [X]


If "Yes" is marked, indicate below the file number assigned to the registrant in
connection with Rule 12g-32(b):82-_____________________



MISCELLANEOUS

MAJOR SHAREHOLDER NOTIFICATION

In accordance with Section 29 of the Securities Trading Act, Novo Nordisk hereby
reports that Capital  Group  Companies on 12 October 2007  informed Novo Nordisk
that Capital  Group  Companies  now holds  48,127,241 B shares of DKK 2 equal to
14.88% of the total share capital in Novo Nordisk.

Novo Nordisk is a healthcare  company and a world leader in diabetes  care.  The
company has the broadest diabetes product  portfolio in the industry,  including
the most  advanced  products  within the area of insulin  delivery  systems.  In
addition,  Novo Nordisk has a leading  position within areas such as haemostasis
management, growth hormone therapy and hormone replacement therapy. Novo Nordisk
manufactures  and  markets  pharmaceutical  products  and  services  that make a
significant  difference to patients,  the medical  profession and society.  With
headquarters in Denmark,  Novo Nordisk employs approximately 25,800 employees in
79 countries, and markets its products in 179 countries. Novo Nordisk's B shares
are listed on the stock exchanges in Copenhagen and London.  Its ADRs are listed
on the New York Stock  Exchange  under the symbol 'NVO'.  For more  information,
visit novonordisk.com.


FURTHER INFORMATION:

Media:                               Investors:
Outside North America:               Outside North America:
Elin K Hansen                        Mads Veggerby Lausten
Tel (direct): (+45) 4442 3450        Tel (direct): (+45) 4443 7919
ekh@novonordisk.com                  mlau@novonordisk.com

                                     Hans Rommer
                                     Tel (direct): (+45) 4442 4765
                                     hrmm@novonordisk.com

In North America:                    In North America:
Sean Clements                        Christian Qvist Frandsen
Tel (direct): (+1) 609 514 8316      Tel (direct): (+1) 609 919 7937
secl@novonordisk.com                 cqfr@novonordisk.com

Stock Exchange Announcement no 28/2007



                                   SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf of the
undersigned, thereunto duly authorized.

Date: OCTOBER 25, 2007                        NOVO NORDISK A/S
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                                            Lars Rebien Sorensen,
                                     President and Chief Executive Officer