UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                    FORM 8-K

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

       Date of Report (Date of earliest event reported): November 30, 2005

                         PROVECTUS PHARMACEUTICALS, INC.
             (Exact name of registrant as specified in its charter)

          Nevada                    000-09410                    90-0031917
(State or other jurisdiction       (Commission                 (IRS Employer
     of incorporation)             File Number)              Identification No.)

        7327 Oak Ridge Highway, Suite A
             Knoxville, Tennessee                                37931
    (Address of principal executive offices)                   (Zip Code)

       Registrant's telephone number, including area code: (865) 769-4011

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions:

[  ] Written communications  pursuant to Rule 425 under the Securities Act (17
     CFR 230.425)

[  ] Soliciting  material  pursuant to Rule 14a-12 under the Exchange Act (17
     CFR 240.14a-12)

[  ] Pre-commencement  communications  pursuant  to Rule  14d-2(b)  under the
     Exchange Act (17 CFR 240.14d-2(b))

[  ] Pre-commencement  communications  pursuant  to Rule  13e-4(c)  under the
     Exchange Act (17 CFR 240.13e-4(c))




Item 3.02.  Unregistered Sales of Equity Securities.

On November  29,  2005,  Provectus  Pharmaceuticals,  Inc.,  completed a private
placement  transaction with 30 accredited  investors,  pursuant to which we sold
2,640,992 shares of our common stock at a purchase price of $0.75 per share, for
an aggregate  purchase price of  $1,980,744.00  pursuant to Securities  Purchase
Agreements with each investor.  In connection with the sale of the common stock,
we also issued  warrants  (the  "Warrants")  to the  investors to purchase up to
3,301,240  shares of our common stock at an exercise  price of $0.935 per share.
We paid $198,074.40 to Network 1 Financial  Securities,  Inc. as placement agent
for this transaction.  The form of Securities Purchase Agreement entered into by
each of the  investors  and the form of  Warrant  issued  to the  investors  are
attached hereto as Exhibit 4.1 and 4.2.

We believe that this offering was exempt from the  registration  requirements of
the Securities Act of 1933, as amended (the "Securities  Act") by reason of Rule
506 of Regulation D and Section 4(2) of the Securities  Act, based upon the fact
that the offer and issuance of the common stock and warrants  satisfied  all the
terms and conditions of Rules 501 and 502 of the  Securities  Act, the investors
are financially  sophisticated and had access to complete information concerning
us and  acquired  the  securities  for  investment  and  not  with a view to the
distribution thereof. Proceeds will be used for general corporate purposes.


Item 9.01. Financial Statements and Exhibits.

(c) Exhibits.

     Exhibit
     Number                           Description
-----------------    -----------------------------------------------------------

      4.1            Form of Securities Purchase Agreement

      4.2            Form of Warrant







                                   SIGNATURES


Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


Date:  December 1, 2005


                                            PROVECTUS PHARMACEUTICALS, INC.

                                            By:  /s/ H. Craig Dees
                                               -------------------------------
                                               H. Craig Dees
                                               Chief Executive Officer